Skip to main content

Table 2 Summary of bivariate association analyses between each culture condition for each cytokine using data collected from 818 children in SCAALA Salvador

From: Applied immuno-epidemiological research: an approach for integrating existing knowledge into the statistical analysis of multiple immune markers

Cytokine Measure ASC BLOM DERM MITO
IFN-γ BLOM γ = 0.21, - - -
P = 0.144
  DERM γ = 0.77***, γ = 0.73**, - -
P = <0.001 P = <0.001
  MITO γ = -0.24, γ = 0.26*, γ = 0.09, -
P = 0.667 P = 0.016 P = 0.653
  NC γ = 0.29*, γ = 0.05, γ = 0.11, γ = -0.84***,
P = 0.242 P = 0.593 P = 0.412 P = <0.001
IL-5 BLOM γ = -0.05, - - -
P = 0.585
  DERM γ = 0.35*, γ = 0.94***, - -
P = 0.057 P = <0.001
  MITO γ = 0.26*, γ = -0.21, γ = 0.19, -
P = 0.047 P = 0.234 P = 0.568
  NC γ = 0.38*, γ = 0.61**, γ = 0.76***, γ = 0.09,
P = <0.001 P = <0.001 P = <0.001 P = 0.405
IL-13 BLOM γ = 0.83***, - - -
P = <0.001
  DERM γ = 0.83***, γ = 0.85***, - -
P = <0.001 P = <0.001
  MITO γ = 0.47*, γ = 0.28*, γ = 0.52**, -
P = <0.001 P = 0.016 P = <0.001
  NC γ = 0.43*, γ = 0.70**, γ = 0.45*, γ = 0.09,
P = <0.001 P = <0.001 P = <0.001 P = 0.005
IL-10 BLOM γ = 0.28*, - - -
P = 0.510
  DERM γ = 0.69**, γ = 0.35*, - -
P = <0.001 P = <0.001
  MITO γ = 0.26*, γ = 0.93***, γ = 0.43*, -
P = 0.326 P = <0.001 P = <0.001
  NC γ = -0.03, γ = -0.95***, γ = -0.35*, γ = -0.96***,
P = 0.468 P = <0.001 P = 0.008 P = <0.001
  1. ASC: response in cell culture stimulated by A. lumbricoides, BLOM: response in cell culture stimulated by B. tropicalis, DERM: response in cell culture stimulated by D. pteronyssinus, MITO: response in cell culture stimulated by pokeweed mitogen, NC: response in nonstimulated cell culture; γ: Goodman and Kruskal’s γ, P: P-value of chi-square test of independence; Strength of association: * … weak (0.25 < |γ| < =0.5)
  2. ** … moderate (0.50 < |γ| < =0.75); *** … strong (0.75 < |γ| < =1); Significant estimates (P<0.05) are shown in bold