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Table 6 Results of interdependence analysis among the immunological summary scores

From: Applied immuno-epidemiological research: an approach for integrating existing knowledge into the statistical analysis of multiple immune markers

Immune response   Th2 response T-Reg response
  Measure ANTI MITO ANTI MITO NC
Th1 response ANTI γ = 0.06, P = 0.248 γ = 0.25*, P < 0.001 γ = 0.33*, P = 0.011 γ = 0.14, P = 0.504 γ = 0.11, P = 0.302
  MITO γ = -0.01, P = 0.723 γ = 0.59**, P < 0.001 γ = 0.42*, P < 0.001 γ = 0.46*, P < 0.001 γ = 0.26*, P = 0.021
Th2 response ANTI - - γ = -0.02, P = 0.509 γ = -0.13, P = 0.458 γ = 0.30*, P = 0.008
  MITO - - γ = 0.36*, P < 0.001 γ = 0.26*, P < 0.001 γ = 0.10, P = 0.280
Th1/Th2 balance ANTI - - γ = 0.14, P = 0.030 γ = -0.01, P = 0.437 γ = 0.20, P = 0.387
  MITO - - γ = 0.39*, P < 0.001 γ = 0.17, P < 0.001 γ = 0.22, P = 0.313
  1. ANTI: Maximum immune response observed in cell cultures stimulated by B. tropicalis or D. pteronyssinus, MITO: response in cell cultures stimulated by pokeweed mitogen, γ: Goodman and Kruskal’s γ, P: P-value of chi-square test of independence, significant associations shown in bold; strength of association: * … weak (0.25 < |γ| < =0.5)
  2. ** … moderate (0.50 < |γ| < =0.75), *** … strong (0.75 < |γ| < =1); Significant estimates (P<0.05) are shown in bold