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Fig. 4 | BMC Immunology

Fig. 4

From: Developmental stage-specific effects of Pim-1 dysregulation on murine bone marrow B cell development

Fig. 4

Impact of Eμ-Pim1Tg or Pim1-deficiency on primitive hematopoietic and myeloid-erythroid progenitor subsets in bone marrow. a Flow cytometry profile and gating strategy for HSC, Flt3+ MPP, CMP, GMP, and MEP. Bar graphs depict absolute numbers or frequencies of the various progenitor subsets. b Percentage of LSK+ in total BM. c–d Absolute number of HSC or MPP in BM. e–g Frequencies of CMP, MEP, or GMP within the Lin- ckithi Sca1- subset. h–j Absolute numbers of CMP, MEP, or GMP in BM. k–m Frequencies of CMP, MEP, or GMP in BM. Data represents the mean ± SEM of 3–10 mice per group. * denotes p < 0.05 and ** denotes p < 0.005

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