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Table 1 Statistical analysis of data included in HLAsupE

From: HLAsupE: an integrated database of HLA supertype-specific epitopes to aid in the development of vaccines with broad coverage of the human population

Label Supertype SupE SupB T-cell activity HLA-binding
P N C P N
A A1 1136 6839 108 2518 9 2817 10175
B A2 4124 15625 1615 2465 182 13623 19297
C A3 1904 9397 259 7519 108 9190 15557
D A24 1599 4341 230 2526 16 1714 4280
E B7 1224 6229 470 1730 79 3232 7488
F B8 35 3434 31 4 -- 1489 2402
G B27 119 3952 106 30 2 1333 5492
H B44 1256 8354 148 4254 5 6368 6642
I B58 95 5151 98 4 2 2414 5466
J B62 165 5224 80 82 3 2362 4385
K C1 18 619 21 -- -- 580 63
L C4 48 1299 45 3 -- 560 791
M A01A03 8 2164 6 1 1 586 1578
N A01A24 664 2145 27 636 1 858 1287
O DP 173 1225 112 74 2 1115 3984
P DQ1 337 1752 174 164 14 1005 2239
Q DQ2 139 1630 140 34 2 507 1343
R DQ3 332 1760 187 247 9 1113 2840
S DQA -- 90 -- -- -- -- 360
T DR1 1604 10262 1373 510 33 8713 7902
U DR3 620 3741 421 232 14 1577 5120
V DR4 1353 5082 1104 446 29 4751 6827
W DR5 549 4545 531 121 2 3970 6359
X DR9 387 2887 335 57 2 2075 2681
  SUM 17889 107747 7621 23657 515 71952 124558
31793 196510
  1. SupE and SupB: the statistics of unique records restored in the HLA supertype-specific epitope data block and the HLA supertype-specific binding peptide data block. The statistics on T-cell activity and HLA-binding capacity, which represent the number of HLA-peptide complexes with experimentally verified activity, were derived from non-redundant records. P, N and C represent positive, negative and contradictory records, respectively