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Table 1 Statistical analysis of data included in HLAsupE

From: HLAsupE: an integrated database of HLA supertype-specific epitopes to aid in the development of vaccines with broad coverage of the human population

Label

Supertype

SupE

SupB

T-cell activity

HLA-binding

P

N

C

P

N

A

A1

1136

6839

108

2518

9

2817

10175

B

A2

4124

15625

1615

2465

182

13623

19297

C

A3

1904

9397

259

7519

108

9190

15557

D

A24

1599

4341

230

2526

16

1714

4280

E

B7

1224

6229

470

1730

79

3232

7488

F

B8

35

3434

31

4

--

1489

2402

G

B27

119

3952

106

30

2

1333

5492

H

B44

1256

8354

148

4254

5

6368

6642

I

B58

95

5151

98

4

2

2414

5466

J

B62

165

5224

80

82

3

2362

4385

K

C1

18

619

21

--

--

580

63

L

C4

48

1299

45

3

--

560

791

M

A01A03

8

2164

6

1

1

586

1578

N

A01A24

664

2145

27

636

1

858

1287

O

DP

173

1225

112

74

2

1115

3984

P

DQ1

337

1752

174

164

14

1005

2239

Q

DQ2

139

1630

140

34

2

507

1343

R

DQ3

332

1760

187

247

9

1113

2840

S

DQA

--

90

--

--

--

--

360

T

DR1

1604

10262

1373

510

33

8713

7902

U

DR3

620

3741

421

232

14

1577

5120

V

DR4

1353

5082

1104

446

29

4751

6827

W

DR5

549

4545

531

121

2

3970

6359

X

DR9

387

2887

335

57

2

2075

2681

 

SUM

17889

107747

7621

23657

515

71952

124558

31793

196510

  1. SupE and SupB: the statistics of unique records restored in the HLA supertype-specific epitope data block and the HLA supertype-specific binding peptide data block. The statistics on T-cell activity and HLA-binding capacity, which represent the number of HLA-peptide complexes with experimentally verified activity, were derived from non-redundant records. P, N and C represent positive, negative and contradictory records, respectively