Fig. 3

HIV-1-specific CTL kinetics in different subjects. a Subject 2, b Subject 1, c Subject 3, d Subject 4, e Subject 5, f Subject 12, g Subject 6, h Subject 9, i Subject 11, j Subject 7, k Subject 10, l Subject 8, m Subject 13, n Subject 14, o Subject 15. HIV-1-specific CD8⁺ T-cell against 18 mer overlapping peptides and optimal epitopes are shown as solid lines. Viral loads are shown as dotted lines. Epitopes containing OLPs (overlapping peptides) indicates that it was an 18 mer overlapping peptide, and containing HLA type indicates that it was an optimal epitope restricted by a certain HLA type. Position and sequence of the optimal epitopes see Additional file 2: Table S2. Colored lines represent different protein responses in each subject. Red, green and yellow lines represent Gag, Pol and Nef responses, respectively