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Table 3 Efficacy and modalities of treatment at baseline and 9 months

From: Treatment with Hizentra in patients with primary and secondary immunodeficiencies: a real-life, non-interventional trial

 

Hizentra

N = 117

Dose at baseline (g/kg/injection), N

113

 Mean ± SD

0.2 ± 0.9

 Median [range]

0.1 [0.0;7.0]

Dose at follow-up (g/kg/injection), N

113

 Mean ± SD

0.3 ± 1.0

 Median [range]

0.1 [0.0;7.0]

Schedule of injections at baseline, N

115

  ≤ 7 days, n (%)

111 (96.5 %)

  > 7 days, n (%)

4 (3.5 %)

Schedule of injections at follow-up, N

116

  ≤ 7 days, n (%)

107 (92.2 %)

  > 7 days, n (%)

9 (7.8 %)

Trough IgG titer at baseline (g/L), N

106

 Mean ± SD

9.0 ± 6.6

 Median [range]

7.7 [0.1;49.5]

Trough IgG titers (g/L) at follow-up, N

95

 Mean ± SD

9.0 ± 3.3

 Median [range]

8.3 [3.4;24.0]

Number of infections at follow-up, N

99

 Mean ± SD

1.0 ± 1.6

 Median [range]

0.0 [0.0;8.0]

Yearly rate of infection, mean ± SD

1.2 ± 1.9

Worsening of immunodeficiency at follow-up, N

98

 Yes, n (%)

1 (5.3 %)

  1. IgG immunoglobulin G, SD standard deviationc