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Table 1 PPRHs designed against the CD47 and SIRPα gene, as well as the scrambled PPRH

From: Silencing of CD47 and SIRPα by Polypurine reverse Hoogsteen hairpins to promote MCF-7 breast cancer cells death by PMA-differentiated THP-1 cells

PPRHs against CD47 gene
 Name Sequence (5′-3′)
 HpCD47I3-T
 HpCd47Pr-T
PPRHs against SIRPα gene
 Name Sequence (5′-3′)
 HpSIRPα-Pr-C
 HpSIRPα-I7-T
Control PPRHs
 Name Sequence (5′-3′)
 Hp-Sc
  1. Abbreviations are
  2. -Hp PPRH hairpin
  3. -Location within the gene sequence: Pr for promoter; I for intron and number indicates which intron
  4. - Type of PPRH: −T for Template-PPRHs, −C for Coding-PPRHs and –Sc for scrambled PPRHs
  5. - Letters in bold indicate polypirimidine interruptions in the sequence