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Fig. 8 | BMC Immunology

Fig. 8

From: A new high-throughput sequencing method for determining diversity and similarity of T cell receptor (TCR) α and β repertoires and identifying potential new invariant TCR α chains

Fig. 8

Similarity of TRA and TRB repertoires in healthy individuals. The occurrence frequency of TCR sequence reads shared between all pairs of 20 individuals was calculated (Additional file 1: Tables S5 and S6). Mean percentage frequency of shared reads were compared between TRA and TRB (left, n = 380). Similarity index, Morisita-Horn index, was calculated with the R program according to a formula described in Materials and Methods. There were significant differences in the frequency of shared reads and similarity index between TRA and TRB (P < 0.001 and P < 0.001, respectively, Mann–Whitney U-test)

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