Fig. 1
Intracaecal Model of Cancer a Mice were anaesthetised and a laparotomy performed. The caecum was exteriorised and tumour cells were injected into the caecal cell wall under 10× magnification. The caecum was returned to the abdominal cavity and the incision was sutured. b 1 × 105 B16-luc cells were injected intracaecally as described. Luciferin was administered to mice and bioluminescence was detected 10, 15 and 22 days later. Data shows a single representative experiment of two. c 2 × 105 B16-luc cells were injected subcutaneously (top) or intracaecally (bottom). Correlation of bioluminescent signal produced (arbitrary units/mm2) to tumour volume are shown. Data show a single representative experiment. Each experiment was performed twice