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Fig. 3 | BMC Immunology

Fig. 3

From: Chitosan gel vaccine protects against tumour growth in an intracaecal mouse model of cancer by modulating systemic immune responses

Fig. 3

Vaccination with a sustained release gel reduces the frequency of tumour development. Mice received adoptive transfer of OT-I lymphocytes and were not vaccinated or were vaccinated with antigen in a chitosan gel (Gel + OVA), the gel alone (Gel) or with antigen pulsed-DC (DC + OVA) then challenged intracaecally with B16-OVA 30 days later. a Percentage of mice with visible tumours and b mean volume of tumours at day 21. Data are shown as mean ± standard deviation, Data pooled from two individual experiments, n = 8–9. One-way ANOVA with Tukey post-hoc test was performed. **P < 0.01

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