Fig. 3From: Lipoproteins attenuate TLR2 and TLR4 activation by bacteria and bacterial ligands with differences in affinity and kineticsEffect of HSdelip or HSdelip supplemented with VLDL, LDL or HDL on TNFα, B. breve or FSL-1 induced NFκB activity. HEK-TLR2-TLR6 cells were incubated with B. breve, FSL-1 or TNFα in the presence of HSdelip or HSdelip supplemented with a dose range of the lipoprotein fractions HDL, LDL or VLDL. TLR2/6 activity in response to B. breve (a) or FSL-1 (b) was dose-dependently inhibited by the different lipoprotein fractions. c None of the lipoprotein fractions inhibited the TNFα induced NFκB activity. Each value represents mean ± SD of triplicates. The experiment shown is representative of three separate experiments. *: p < 0.05 **:P < 0.01 ***:P < 0.001 determined by comparison with HSdelipBack to article page