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Fig. 4 | BMC Immunology

Fig. 4

From: Immune modulation of CD4+CD25+ regulatory T cells by zoledronic acid

Fig. 4

Influence of ZA on mRNA expression by Treg cells. mRNA levels were evaluated by qRT-PCR in Treg cells treated with 0, 50, 100 μM ZA for 6 h. The gene expression values were normalized to GAPDH expression. The relative mRNA expression of (a) CCR4, (b) Foxp3, (c) TGFβ and (d) PD-1 was calculated from Treg cells treated with ZA compared with untreated Treg cells. Values shown are means ± SEM of results from four independent experiments performed in duplicate. *p < 0.05

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