TY - JOUR AU - Hajishengallis, G. AU - Darveau, R. P. AU - Curtis, M. A. PY - 2012 DA - 2012// TI - The keystone-pathogen hypothesis JO - Nat Rev Microbiol VL - 10 UR - https://doi.org/10.1038/nrmicro2873 DO - 10.1038/nrmicro2873 ID - Hajishengallis2012 ER - TY - JOUR AU - Darveau, R. P. AU - Cunningham, M. D. AU - Bailey, T. AU - Seachord, C. AU - Ratcliffe, K. AU - Bainbridge, B. AU - Dietsch, M. AU - Page, R. C. AU - Aruffo, A. PY - 1995 DA - 1995// TI - Ability of bacteria associated with chronic inflammatory disease to stimulate E-selectin expression and promote neutrophil adhesion JO - Infect Immun VL - 63 ID - Darveau1995 ER - TY - JOUR AU - Deshpande, R. G. AU - Khan, M. AU - Genco, C. A. PY - 1998 DA - 1998// TI - Invasion strategies of the oral pathogen porphyromonas gingivalis: implications for cardiovascular disease JO - Invasion Metastasis VL - 18 UR - https://doi.org/10.1159/000024499 DO - 10.1159/000024499 ID - Deshpande1998 ER - TY - JOUR AU - Socransky, S. S. AU - Haffajee, A. D. PY - 2005 DA - 2005// TI - Periodontal microbial ecology JO - Periodontol 2000 VL - 38 UR - https://doi.org/10.1111/j.1600-0757.2005.00107.x DO - 10.1111/j.1600-0757.2005.00107.x ID - Socransky2005 ER - TY - JOUR AU - Dobrovolskaia, M. A. AU - Medvedev, A. E. AU - Thomas, K. E. AU - Cuesta, N. AU - Toshchakov, V. AU - Ren, T. AU - Cody, M. J. AU - Michalek, S. M. AU - Rice, N. R. AU - Vogel, S. N. PY - 2003 DA - 2003// TI - Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR “homotolerance” versus “heterotolerance” on NF-kappa B signaling pathway components JO - J Immunol VL - 170 UR - https://doi.org/10.4049/jimmunol.170.1.508 DO - 10.4049/jimmunol.170.1.508 ID - Dobrovolskaia2003 ER - TY - JOUR AU - Ulevitch, R. J. AU - Tobias, P. S. PY - 1995 DA - 1995// TI - Receptor-dependent mechanisms of cell stimulation by bacterial endotoxin JO - Annu Rev Immunol VL - 13 UR - https://doi.org/10.1146/annurev.iy.13.040195.002253 DO - 10.1146/annurev.iy.13.040195.002253 ID - Ulevitch1995 ER - TY - JOUR AU - Hajishengallis, G. AU - Sojar, H. AU - Genco, R. J. AU - DeNardin, E. PY - 2004 DA - 2004// TI - Intracellular signaling and cytokine induction upon interactions of Porphyromonas gingivalis fimbriae with pattern-recognition receptors JO - Immunol Invest VL - 33 UR - https://doi.org/10.1081/IMM-120030917 DO - 10.1081/IMM-120030917 ID - Hajishengallis2004 ER - TY - STD TI - Huynh J, Scholz GM, Aw J, Kwa MQ, Achuthan A, Hamilton JA, Reynolds EC. IRF6 Regulates the Expression of IL-36 gamma by Human Oral Epithelial Cells in Response to Porphyromonas gingivalis. J Immunol. 2016;196(5):2230–8. ID - ref8 ER - TY - JOUR AU - Sandros, J. AU - Karlsson, C. AU - Lappin, D. F. AU - Madianos, P. N. AU - Kinane, D. F. AU - Papapanou, P. N. PY - 2000 DA - 2000// TI - Cytokine responses of oral epithelial cells to Porphyromonas gingivalis infection JO - J Dent Res VL - 79 UR - https://doi.org/10.1177/00220345000790101301 DO - 10.1177/00220345000790101301 ID - Sandros2000 ER - TY - JOUR AU - Medzhitov, R. PY - 2001 DA - 2001// TI - Toll-like receptors and innate immunity JO - Nat Rev Immunol VL - 1 UR - https://doi.org/10.1038/35100529 DO - 10.1038/35100529 ID - Medzhitov2001 ER - TY - JOUR AU - Medzhitov, R. AU - Janeway, C. PY - 2000 DA - 2000// TI - Innate immune recognition: mechanisms and pathways JO - Immunol Rev VL - 173 UR - https://doi.org/10.1034/j.1600-065X.2000.917309.x DO - 10.1034/j.1600-065X.2000.917309.x ID - Medzhitov2000 ER - TY - JOUR AU - Kawai, T. AU - Akira, S. PY - 2010 DA - 2010// TI - The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors JO - Nat Immunol VL - 11 UR - https://doi.org/10.1038/ni.1863 DO - 10.1038/ni.1863 ID - Kawai2010 ER - TY - JOUR AU - Ricklin, D. AU - Hajishengallis, G. AU - Yang, K. AU - Lambris, J. D. PY - 2010 DA - 2010// TI - Complement: a key system for immune surveillance and homeostasis JO - Nat Immunol VL - 11 UR - https://doi.org/10.1038/ni.1923 DO - 10.1038/ni.1923 ID - Ricklin2010 ER - TY - JOUR AU - Bourhis, L. L. AU - Werts, C. PY - 2007 DA - 2007// TI - Role of Nods in bacterial infection JO - Microbes Infect VL - 9 UR - https://doi.org/10.1016/j.micinf.2007.01.014 DO - 10.1016/j.micinf.2007.01.014 ID - Bourhis2007 ER - TY - JOUR AU - Medzhitov, R. AU - Janeway, C. PY - 2000 DA - 2000// TI - The Toll receptor family and microbial recognition JO - Trends Microbiol VL - 8 UR - https://doi.org/10.1016/S0966-842X(00)01845-X DO - 10.1016/S0966-842X(00)01845-X ID - Medzhitov2000 ER - TY - JOUR AU - Lotze, M. T. AU - Zeh, H. J. AU - Rubartelli, A. AU - Sparvero, L. J. AU - Amoscato, A. A. AU - Washburn, N. R. AU - Devera, M. E. AU - Liang, X. AU - Tor, M. AU - Billiar, T. PY - 2007 DA - 2007// TI - The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity JO - Immunol Rev VL - 220 UR - https://doi.org/10.1111/j.1600-065X.2007.00579.x DO - 10.1111/j.1600-065X.2007.00579.x ID - Lotze2007 ER - TY - JOUR AU - Martinon, F. AU - Mayor, A. AU - Tschopp, J. PY - 2009 DA - 2009// TI - The inflammasomes: guardians of the body JO - Annu Rev Immunol VL - 27 UR - https://doi.org/10.1146/annurev.immunol.021908.132715 DO - 10.1146/annurev.immunol.021908.132715 ID - Martinon2009 ER - TY - JOUR AU - Martinon, F. AU - Gaide, O. AU - Petrilli, V. AU - Mayor, A. AU - Tschopp, J. PY - 2007 DA - 2007// TI - NALP inflammasomes: a central role in innate immunity JO - Semin Immunopathol VL - 29 UR - https://doi.org/10.1007/s00281-007-0079-y DO - 10.1007/s00281-007-0079-y ID - Martinon2007 ER - TY - JOUR AU - Said-Sadier, N. AU - Ojcius, D. M. PY - 2012 DA - 2012// TI - Alarmins, inflammasomes and immunity JO - Biomed J VL - 35 UR - https://doi.org/10.4103/2319-4170.104408 DO - 10.4103/2319-4170.104408 ID - Said-Sadier2012 ER - TY - JOUR AU - Yilmaz, O. AU - Sater, A. A. AU - Yao, L. AU - Koutouzis, T. AU - Pettengill, M. AU - Ojcius, D. M. PY - 2010 DA - 2010// TI - ATP-dependent activation of an inflammasome in primary gingival epithelial cells infected by Porphyromonas gingivalis JO - Cell Microbiol VL - 12 UR - https://doi.org/10.1111/j.1462-5822.2009.01390.x DO - 10.1111/j.1462-5822.2009.01390.x ID - Yilmaz2010 ER - TY - JOUR AU - Johnson, L. AU - Atanasova, K. R. AU - Bui, P. Q. AU - Lee, J. AU - Hung, S. C. AU - Yilmaz, O. AU - Ojcius, D. M. PY - 2015 DA - 2015// TI - Porphyromonas gingivalis attenuates ATP-mediated inflammasome activation and HMGB1 release through expression of a nucleoside-diphosphate kinase JO - Microbes Infect VL - 17 UR - https://doi.org/10.1016/j.micinf.2015.03.010 DO - 10.1016/j.micinf.2015.03.010 ID - Johnson2015 ER - TY - JOUR AU - Handfield, M. AU - Mans, J. J. AU - Zheng, G. AU - Lopez, M. C. AU - Mao, S. AU - Progulske-Fox, A. AU - Narasimhan, G. AU - Baker, H. V. AU - Lamont, R. J. PY - 2005 DA - 2005// TI - Distinct transcriptional profiles characterize oral epithelium-microbiota interactions JO - Cell Microbiol VL - 7 UR - https://doi.org/10.1111/j.1462-5822.2005.00513.x DO - 10.1111/j.1462-5822.2005.00513.x ID - Handfield2005 ER - TY - JOUR AU - Hasegawa, Y. AU - Mans, J. J. AU - Mao, S. AU - Lopez, M. C. AU - Baker, H. V. AU - Handfield, M. AU - Lamont, R. J. PY - 2007 DA - 2007// TI - Gingival epithelial cell transcriptional responses to commensal and opportunistic oral microbial species JO - Infect Immun VL - 75 UR - https://doi.org/10.1128/IAI.01957-06 DO - 10.1128/IAI.01957-06 ID - Hasegawa2007 ER - TY - JOUR AU - Kinane, D. F. AU - Galicia, J. C. AU - Gorr, S. U. AU - Stathopoulou, P. G. AU - Benakanakere, M. PY - 2008 DA - 2008// TI - P. gingivalis interactions with epithelial cells JO - Front Biosci VL - 13 UR - https://doi.org/10.2741/2736 DO - 10.2741/2736 ID - Kinane2008 ER - TY - JOUR AU - Lee, J. Y. AU - Suh, J. S. AU - Kim, J. M. AU - Kim, J. H. AU - Park, H. J. AU - Park, Y. J. AU - Chung, C. P. PY - 2015 DA - 2015// TI - Identification of a cell-penetrating peptide domain from human beta-defensin 3 and characterization of its anti-inflammatory activity JO - Int J Nanomedicine VL - 10 ID - Lee2015 ER - TY - JOUR AU - Cohen, N. AU - Morisset, J. AU - Emilie, D. PY - 2004 DA - 2004// TI - Induction of tolerance by Porphyromonas gingivalis on APCS: a mechanism implicated in periodontal infection JO - J Dent Res VL - 83 UR - https://doi.org/10.1177/154405910408300515 DO - 10.1177/154405910408300515 ID - Cohen2004 ER - TY - JOUR AU - Groeger, S. AU - Domann, E. AU - Gonzales, J. R. AU - Chakraborty, T. AU - Meyle, J. PY - 2011 DA - 2011// TI - B7-H1 and B7-DC receptors of oral squamous carcinoma cells are upregulated by Porphyromonas gingivalis JO - Immunobiology VL - 216 UR - https://doi.org/10.1016/j.imbio.2011.05.005 DO - 10.1016/j.imbio.2011.05.005 ID - Groeger2011 ER - TY - JOUR AU - Dong, H. AU - Zhu, G. AU - Tamada, K. AU - Chen, L. PY - 1999 DA - 1999// TI - B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion JO - Nat Med VL - 5 UR - https://doi.org/10.1038/70932 DO - 10.1038/70932 ID - Dong1999 ER - TY - JOUR AU - Freeman, G. J. AU - Long, A. J. AU - Iwai, Y. AU - Bourque, K. AU - Chernova, T. AU - Nishimura, H. AU - Fitz, L. J. AU - Malenkovich, N. AU - Okazaki, T. AU - Byrne, M. C. PY - 2000 DA - 2000// TI - Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation JO - J Exp Med VL - 192 UR - https://doi.org/10.1084/jem.192.7.1027 DO - 10.1084/jem.192.7.1027 ID - Freeman2000 ER - TY - JOUR AU - Chen, Y. AU - Zhang, J. AU - Guo, G. AU - Ruan, Z. AU - Jiang, M. AU - Wu, S. AU - Guo, S. AU - Fei, L. AU - Tang, Y. AU - Yang, C. PY - 2009 DA - 2009// TI - Induced B7-H1 expression on human renal tubular epithelial cells by the sublytic terminal complement complex C5b-9 JO - Mol Immunol VL - 46 UR - https://doi.org/10.1016/j.molimm.2008.10.026 DO - 10.1016/j.molimm.2008.10.026 ID - Chen2009 ER - TY - JOUR AU - LaGier, A. J. AU - Pober, J. S. PY - 2006 DA - 2006// TI - Immune accessory functions of human endothelial cells are modulated by overexpression of B7-H1 (PDL1) JO - Hum Immunol VL - 67 UR - https://doi.org/10.1016/j.humimm.2006.04.013 DO - 10.1016/j.humimm.2006.04.013 ID - LaGier2006 ER - TY - JOUR AU - Yamazaki, T. AU - Akiba, H. AU - Iwai, H. AU - Matsuda, H. AU - Aoki, M. AU - Tanno, Y. AU - Shin, T. AU - Tsuchiya, H. AU - Pardoll, D. M. AU - Okumura, K. PY - 2002 DA - 2002// TI - Expression of programmed death 1 ligands by murine T cells and APC JO - J Immunol VL - 169 UR - https://doi.org/10.4049/jimmunol.169.10.5538 DO - 10.4049/jimmunol.169.10.5538 ID - Yamazaki2002 ER - TY - JOUR AU - Ishida, Y. AU - Agata, Y. AU - Shibahara, K. AU - Honjo, T. PY - 1992 DA - 1992// TI - Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death JO - Embo J VL - 11 ID - Ishida1992 ER - TY - JOUR AU - Wang, S. AU - Chen, L. PY - 2004 DA - 2004// TI - T lymphocyte co-signaling pathways of the B7-CD28 family JO - Cell Mol Immunol VL - 1 ID - Wang2004 ER - TY - JOUR AU - Dong, H. AU - Strome, S. E. AU - Salomao, D. R. AU - Tamura, H. AU - Hirano, F. AU - Flies, D. B. AU - Roche, P. C. AU - Lu, J. AU - Zhu, G. AU - Tamada, K. PY - 2002 DA - 2002// TI - Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion JO - Nat Med VL - 8 ID - Dong2002 ER - TY - JOUR AU - Subudhi, S. K. AU - Zhou, P. AU - Yerian, L. M. AU - Chin, R. K. AU - Lo, J. C. AU - Anders, R. A. AU - Sun, Y. AU - Chen, L. AU - Wang, Y. AU - Alegre, M. L. PY - 2004 DA - 2004// TI - Local expression of B7-H1 promotes organ-specific autoimmunity and transplant rejection JO - J Clin Invest VL - 113 UR - https://doi.org/10.1172/JCI19210 DO - 10.1172/JCI19210 ID - Subudhi2004 ER - TY - JOUR AU - Agata, Y. AU - Kawasaki, A. AU - Nishimura, H. AU - Ishida, Y. AU - Tsubata, T. AU - Yagita, H. AU - Honjo, T. PY - 1996 DA - 1996// TI - Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes JO - Int Immunol VL - 8 UR - https://doi.org/10.1093/intimm/8.5.765 DO - 10.1093/intimm/8.5.765 ID - Agata1996 ER - TY - JOUR AU - Kronenberg, M. AU - Rudensky, A. PY - 2005 DA - 2005// TI - Regulation of immunity by self-reactive T cells JO - Nature VL - 435 UR - https://doi.org/10.1038/nature03725 DO - 10.1038/nature03725 ID - Kronenberg2005 ER - TY - JOUR AU - Sakaguchi, S. AU - Yamaguchi, T. AU - Nomura, T. AU - Ono, M. PY - 2008 DA - 2008// TI - Regulatory T cells and immune tolerance JO - Cell VL - 133 UR - https://doi.org/10.1016/j.cell.2008.05.009 DO - 10.1016/j.cell.2008.05.009 ID - Sakaguchi2008 ER - TY - JOUR AU - Tang, Q. AU - Bluestone, J. A. PY - 2008 DA - 2008// TI - The Foxp3+ regulatory T cell: a jack of all trades, master of regulation JO - Nat Immunol VL - 9 UR - https://doi.org/10.1038/ni1572 DO - 10.1038/ni1572 ID - Tang2008 ER - TY - JOUR AU - Baecher-Allan, C. AU - Brown, J. A. AU - Freeman, G. J. AU - Hafler, D. A. PY - 2001 DA - 2001// TI - CD4 + CD25high regulatory cells in human peripheral blood JO - J Immunol VL - 167 UR - https://doi.org/10.4049/jimmunol.167.3.1245 DO - 10.4049/jimmunol.167.3.1245 ID - Baecher-Allan2001 ER - TY - JOUR AU - Kitazawa, Y. AU - Fujino, M. AU - Wang, Q. AU - Kimura, H. AU - Azuma, M. AU - Kubo, M. AU - Abe, R. AU - Li, X. K. PY - 2007 DA - 2007// TI - Involvement of the programmed death-1/programmed death-1 ligand pathway in CD4 + CD25+ regulatory T-cell activity to suppress alloimmune responses JO - Transplantation VL - 83 UR - https://doi.org/10.1097/01.tp.0000256293.90270.e8 DO - 10.1097/01.tp.0000256293.90270.e8 ID - Kitazawa2007 ER - TY - JOUR AU - Francisco, L. M. AU - Salinas, V. H. AU - Brown, K. E. AU - Vanguri, V. K. AU - Freeman, G. J. AU - Kuchroo, V. K. AU - Sharpe, A. H. PY - 2009 DA - 2009// TI - PD-L1 regulates the development, maintenance, and function of induced regulatory T cells JO - J Exp Med VL - 206 UR - https://doi.org/10.1084/jem.20090847 DO - 10.1084/jem.20090847 ID - Francisco2009 ER - TY - JOUR AU - Qian, Y. AU - Deng, J. AU - Geng, L. AU - Xie, H. AU - Jiang, G. AU - Zhou, L. AU - Wang, Y. AU - Yin, S. AU - Feng, X. AU - Liu, J. PY - 2008 DA - 2008// TI - TLR4 signaling induces B7-H1 expression through MAPK pathways in bladder cancer cells JO - Cancer Invest VL - 26 UR - https://doi.org/10.1080/07357900801941852 DO - 10.1080/07357900801941852 ID - Qian2008 ER - TY - JOUR AU - Allam, J. P. AU - Peng, W. M. AU - Appel, T. AU - Wenghoefer, M. AU - Niederhagen, B. AU - Bieber, T. AU - Berge, S. AU - Novak, N. PY - 2008 DA - 2008// TI - Toll-like receptor 4 ligation enforces tolerogenic properties of oral mucosal Langerhans cells JO - J Allergy Clin Immunol VL - 121 UR - https://doi.org/10.1016/j.jaci.2007.09.045 DO - 10.1016/j.jaci.2007.09.045 ID - Allam2008 ER - TY - JOUR AU - Liu, J. AU - Hamrouni, A. AU - Wolowiec, D. AU - Coiteux, V. AU - Kuliczkowski, K. AU - Hetuin, D. AU - Saudemont, A. AU - Quesnel, B. PY - 2007 DA - 2007// TI - Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway JO - Blood VL - 110 UR - https://doi.org/10.1182/blood-2006-10-051482 DO - 10.1182/blood-2006-10-051482 ID - Liu2007 ER - TY - JOUR AU - Dyke, T. E. PY - 2008 DA - 2008// TI - The management of inflammation in periodontal disease JO - J Periodontol VL - 79 UR - https://doi.org/10.1902/jop.2008.080173 DO - 10.1902/jop.2008.080173 ID - Dyke2008 ER - TY - JOUR AU - Milward, M. R. AU - Chapple, I. L. AU - Wright, H. J. AU - Millard, J. L. AU - Matthews, J. B. AU - Cooper, P. R. PY - 2007 DA - 2007// TI - Differential activation of NF-kappaB and gene expression in oral epithelial cells by periodontal pathogens JO - Clin Exp Immunol VL - 148 UR - https://doi.org/10.1111/j.1365-2249.2007.03342.x DO - 10.1111/j.1365-2249.2007.03342.x ID - Milward2007 ER - TY - JOUR AU - Grenier, D. AU - Tanabe, S. PY - 2010 DA - 2010// TI - Porphyromonas gingivalis gingipains trigger a proinflammatory response in human monocyte-derived macrophages through the p38alpha mitogen-activated protein kinase signal transduction pathway JO - Toxins (Basel) VL - 2 UR - https://doi.org/10.3390/toxins2030341 DO - 10.3390/toxins2030341 ID - Grenier2010 ER - TY - JOUR AU - Cario, E. AU - Rosenberg, I. M. AU - Brandwein, S. L. AU - Beck, P. L. AU - Reinecker, H. C. AU - Podolsky, D. K. PY - 2000 DA - 2000// TI - Lipopolysaccharide activates distinct signaling pathways in intestinal epithelial cell lines expressing Toll-like receptors JO - J Immunol VL - 164 UR - https://doi.org/10.4049/jimmunol.164.2.966 DO - 10.4049/jimmunol.164.2.966 ID - Cario2000 ER - TY - JOUR AU - Qin, H. AU - Wilson, C. A. AU - Lee, S. J. AU - Zhao, X. AU - Benveniste, E. N. PY - 2005 DA - 2005// TI - LPS induces CD40 gene expression through the activation of NF-kappaB and STAT-1alpha in macrophages and microglia JO - Blood VL - 106 UR - https://doi.org/10.1182/blood-2005-02-0759 DO - 10.1182/blood-2005-02-0759 ID - Qin2005 ER - TY - JOUR AU - Darmoul, D. AU - Gratio, V. AU - Devaud, H. AU - Laburthe, M. PY - 2004 DA - 2004// TI - Protease-activated receptor 2 in colon cancer: trypsin-induced MAPK phosphorylation and cell proliferation are mediated by epidermal growth factor receptor transactivation JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M401430200 DO - 10.1074/jbc.M401430200 ID - Darmoul2004 ER - TY - JOUR AU - Fyfe, M. AU - Bergstrom, M. AU - Aspengren, S. AU - Peterson, A. PY - 2005 DA - 2005// TI - PAR-2 activation in intestinal epithelial cells potentiates interleukin-1beta-induced chemokine secretion via MAP kinase signaling pathways JO - Cytokine VL - 31 UR - https://doi.org/10.1016/j.cyto.2005.06.004 DO - 10.1016/j.cyto.2005.06.004 ID - Fyfe2005 ER - TY - JOUR AU - Toubi, E. AU - Shoenfeld, Y. PY - 2004 DA - 2004// TI - Toll-like receptors and their role in the development of autoimmune diseases JO - Autoimmunity VL - 37 UR - https://doi.org/10.1080/08916930410001704944 DO - 10.1080/08916930410001704944 ID - Toubi2004 ER - TY - JOUR AU - Yu, Y. AU - Zeng, H. AU - Lyons, S. AU - Carlson, A. AU - Merlin, D. AU - Neish, A. S. AU - Gewirtz, A. T. PY - 2003 DA - 2003// TI - TLR5-mediated activation of p38 MAPK regulates epithelial IL-8 expression via posttranscriptional mechanism JO - Am J Physiol Gastrointest Liver Physiol VL - 285 UR - https://doi.org/10.1152/ajpgi.00503.2002 DO - 10.1152/ajpgi.00503.2002 ID - Yu2003 ER - TY - JOUR AU - Hennessy, E. J. AU - Parker, A. E. AU - O’Neill, L. A. PY - 2010 DA - 2010// TI - Targeting Toll-like receptors: emerging therapeutics? JO - Nat Rev Drug Discov VL - 9 UR - https://doi.org/10.1038/nrd3203 DO - 10.1038/nrd3203 ID - Hennessy2010 ER - TY - JOUR AU - Roux, P. P. AU - Blenis, J. PY - 2004 DA - 2004// TI - ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions JO - Microbiol Mol Biol Rev VL - 68 UR - https://doi.org/10.1128/MMBR.68.2.320-344.2004 DO - 10.1128/MMBR.68.2.320-344.2004 ID - Roux2004 ER - TY - JOUR AU - Ding, P. H. AU - Wang, C. Y. AU - Darveau, R. P. AU - Jin, L. J. PY - 2013 DA - 2013// TI - Nuclear factor-kappaB and p38 mitogen-activated protein kinase signaling pathways are critically involved in Porphyromonas gingivalis lipopolysaccharide induction of lipopolysaccharide-binding protein expression in human oral keratinocytes JO - Mol Oral Microbiol VL - 28 UR - https://doi.org/10.1111/omi.12010 DO - 10.1111/omi.12010 ID - Ding2013 ER - TY - JOUR AU - Dillon, S. AU - Agrawal, A. AU - Dyke, T. AU - Landreth, G. AU - McCauley, L. AU - Koh, A. AU - Maliszewski, C. AU - Akira, S. AU - Pulendran, B. PY - 2004 DA - 2004// TI - A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells JO - J Immunol VL - 172 UR - https://doi.org/10.4049/jimmunol.172.8.4733 DO - 10.4049/jimmunol.172.8.4733 ID - Dillon2004 ER - TY - JOUR AU - Flood, D. G. AU - Finn, J. P. AU - Walton, K. M. AU - Dionne, C. A. AU - Contreras, P. C. AU - Miller, M. S. AU - Bhat, R. V. PY - 1998 DA - 1998// TI - Immunolocalization of the mitogen-activated protein kinases p42MAPK and JNK1, and their regulatory kinases MEK1 and MEK4, in adult rat central nervous system JO - J Comp Neurol VL - 398 UR - https://doi.org/3.0.CO;2-X DO - 3.0.CO;2-X ID - Flood1998 ER - TY - JOUR AU - Chuang, C. Y. AU - Chen, T. G. AU - Tai, Y. T. AU - Chen, T. L. AU - Lin, Y. H. AU - Tsai, C. H. AU - Chen, R. M. PY - 2011 DA - 2011// TI - Toll-like receptor 2-mediated sequential activation of MyD88 and MAPKs contributes to lipopolysaccharide-induced sp-a gene expression in human alveolar epithelial cells JO - Immunobiology VL - 216 UR - https://doi.org/10.1016/j.imbio.2010.10.009 DO - 10.1016/j.imbio.2010.10.009 ID - Chuang2011 ER - TY - JOUR AU - Leelahavanichkul, K. AU - Amornphimoltham, P. AU - Molinolo, A. A. AU - Basile, J. R. AU - Koontongkaew, S. AU - Gutkind, J. S. PY - 2014 DA - 2014// TI - A role for p38 MAPK in head and neck cancer cell growth and tumor-induced angiogenesis and lymphangiogenesis JO - Mol Oncol VL - 8 UR - https://doi.org/10.1016/j.molonc.2013.10.003 DO - 10.1016/j.molonc.2013.10.003 ID - Leelahavanichkul2014 ER - TY - JOUR AU - Westermarck, J. AU - Li, S. AU - Jaakkola, P. AU - Kallunki, T. AU - Grenman, R. AU - Kahari, V. M. PY - 2000 DA - 2000// TI - Activation of fibroblast collagenase-1 expression by tumor cells of squamous cell carcinomas is mediated by p38 mitogen-activated protein kinase and c-Jun NH2-terminal kinase-2 JO - Cancer Res VL - 60 ID - Westermarck2000 ER - TY - JOUR AU - Tezal, M. AU - Grossi, S. G. AU - Genco, R. J. PY - 2005 DA - 2005// TI - Is periodontitis associated with oral neoplasms? JO - J Periodontol VL - 76 UR - https://doi.org/10.1902/jop.2005.76.3.406 DO - 10.1902/jop.2005.76.3.406 ID - Tezal2005 ER - TY - JOUR AU - Steinhagen, F. AU - McFarland, A. P. AU - Rodriguez, L. G. AU - Tewary, P. AU - Jarret, A. AU - Savan, R. AU - Klinman, D. M. PY - 2013 DA - 2013// TI - IRF-5 and NF-kappaB p50 co-regulate IFN-beta and IL-6 expression in TLR9-stimulated human plasmacytoid dendritic cells JO - Eur J Immunol VL - 43 UR - https://doi.org/10.1002/eji.201242792 DO - 10.1002/eji.201242792 ID - Steinhagen2013 ER - TY - JOUR AU - Barnes, B. J. AU - Moore, P. A. AU - Pitha, P. M. PY - 2001 DA - 2001// TI - Virus-specific activation of a novel interferon regulatory factor, IRF-5, results in the induction of distinct interferon alpha genes JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M101216200 DO - 10.1074/jbc.M101216200 ID - Barnes2001 ER -