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Table 2 Up-regulated genes in SCC-25 cells after stimulation for 24 h with living P. gingivalis W 83.

From: Porphyromonas gingivalis activates NFκB and MAPK pathways in human oral epithelial cells

Gene Symbol

Fold Regulation

Biological Function

IRAK3

2.8

TLR Signaling

IRF5

2.7

RAC1

3.0

TICAM1

2.5

TOLLIP

2.2

RELA

2.7

CASP8

2.8

NLR signaling, Apoptosis

IKBKB *

3.1

NF-κB Pathway

NFKB1

3.6

JUN

3.2

MAPK Pathway

MAP2K1

3.6

MAP2K4 *

2.7

MAPK1

3.3

MAPK14 *

2.7

MAPK8 *

2.6

CCL5

2.2

Chemokines

IL12A

2.4

Cytokines

CASP1

4.9

Apoptosis

  1. Mean values from 3 experiments as x-fold regulation compared to the non-infected control. * = p < 0.05