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Fig. 5 | BMC Immunology

Fig. 5

From: Insight into SNPs and epitopes of E protein of newly emerged genotype-I isolates of JEV from Midnapur, West Bengal, India

Fig. 5

Docking and structure based short listing of antigenic epitopes using human class I MHC (HLA-A i.e. 2X4O.pdb in a) and class II MHC (HLA-DRB1 i.e. 1DLH.pdb in b) crystal structures. Typical sequence and structure of docked peptide (blue color A & B) with white one as mutated residue. PBG indicates peptide binding groove which was mapped using NACCESS procedure [44] (see Materials and Methods for details). Two views per MHC class are shown for better visualization of binding pocket and binding groove. Chains of both classes of MHCs are shown by conventional notations

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