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Fig. 5 | BMC Immunology

Fig. 5

From: Forkhead-box transcription factor 1 affects the apoptosis of natural regulatory T cells by controlling Aven expression

Fig. 5

Detection of apoptosis after knockdown and over-expression of Aven in Treg cells. Expression of the (a) mRNA and (b)protein of Aven in Treg cells 48 h after transfection with Aven siRNA or over-expression plasmid of Foxo1. c Representative result of apoptosis in nTreg and iTreg cells 48 h after transfection with Aven siRNA or over-expression plasmid of Foxo1. Treg cells were stimulated with anti-CD3 (0.01 μg/ml) and anti-CD28 (1.0 μg/ml) in medium during culture. Data are presented as the mean + standard deviation (SD). ***P <0.001

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BMC Immunology

ISSN: 1471-2172

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