Table 5 New restrictions identified from MTB data for which cell lines were not available
From: Experimental validation of the RATE tool for inferring HLA restrictions of T cell epitopes
Epitope | Allele | A+R+ | Relative frequency | p-value |
|---|---|---|---|---|
AAFSRMLSLFFRQHI | DPB1*03:01 | 2 | 13.667 | 0.005 |
AAVLRFQEAANKQKQ | DRB1*15:03 | 3 | 10.600 | 0.000 |
AAVVRFQEAANKQKQ | DRB1*15:03 | 6 | 3.600 | 0.001 |
AEKFKEDVINDFVSS | DQB1*03:03 | 2 | 13.500 | 0.005 |
AGWLAFFRDLVARGL | DRB4*01:03 | 5 | 2.692 | 0.010 |
AHGETVSAVAELIGD | DRB1*15:01 | 4 | 6.480 | 0.001 |
AHGETVSAVAELIGD | DRB5*01:01 | 4 | 3.600 | 0.008 |
ALSRVQSMFLGTGGS | DRB1*15:03 | 3 | 11.857 | 0.000 |
AQAAVVRFQEAANKQ | DRB1*15:03 | 7 | 4.375 | 0.000 |
ARTISEAGQAMASTE | DQB1*03:19 | 5 | 5.303 | 0.000 |
ATSLDTMTQMNQAFR | DQB1*06:01 | 2 | 27.000 | 0.001 |
ATSLDTMTQMNQAFR | DRB1*15:02 | 2 | 27.000 | 0.001 |
AYGSFVRTVSLPVGA | DQB1*02:02 | 5 | 3.661 | 0.003 |
AYGSFVRTVSLPVGA | DRB4*01:03 | 7 | 2.870 | 0.001 |
DLVRAYHSMSSTHEA | DPB1*04:02 | 3 | 5.640 | 0.006 |
HEANTMAMMARDTAE | DPB1*13:01 | 4 | 3.733 | 0.007 |
ILPIAEMSVVAMEFG | DQB1*03:03 | 3 | 10.125 | 0.001 |
ILPIAEMSVVAMEFG | DRB1*04:07 | 2 | 10.125 | 0.009 |
IQGNVTSIHSLLDEG | DRB4*01:03 | 7 | 2.344 | 0.007 |
LENDNQLLYNYPGAL | DRB1*15:02 | 3 | 6.231 | 0.003 |
LRIAAKIYSEADEAW | DQB1*03:19 | 6 | 2.893 | 0.003 |
MHVSFVMAYPEMLAA | DRB1*15:03 | 4 | 5.929 | 0.001 |
MLGHAGDMAGYAGTL | DPB1*13:01 | 2 | 9.333 | 0.010 |
MSQIMYNYPAMLGHA | DQB1*06:01 | 3 | 4.667 | 0.008 |
MSQIMYNYPAMMAHA | DQB1*06:01 | 4 | 3.682 | 0.004 |
MSQIMYNYPAMMAHA | DRB1*15:02 | 4 | 3.682 | 0.004 |
MTSRFMTDPHAMRDM | DQB1*06:01 | 2 | 13.500 | 0.004 |
MTSRFMTDPHAMRDM | DRB1*15:02 | 2 | 13.500 | 0.004 |
MVAAASPYVAWMSVT | DRB1*15:02 | 2 | 17.667 | 0.002 |
MVAAASPYVAWMSVT | DQB1*06:01 | 2 | 11.778 | 0.006 |
QAAVVRFQEAANKQK | DRB1*15:03 | 9 | 3.500 | 0.000 |
RQSGATIADVLAEKE | DRB5*01:01 | 5 | 3.214 | 0.005 |
RRMWASAQNISGAGW | DQB1*06:01 | 2 | 27.000 | 0.001 |
RRMWASAQNISGAGW | DRB1*15:02 | 2 | 27.000 | 0.001 |
VAAAQMWDSVASDLF | DQB1*06:01 | 2 | 11.778 | 0.006 |
VEDEARRMWASAQNI | DQB1*06:01 | 2 | 27.000 | 0.001 |
VEDEARRMWASAQNI | DRB1*15:02 | 2 | 27.000 | 0.001 |
VRFQEAANKQKQELD | DRB1*15:03 | 6 | 5.156 | 0.000 |
YNYPAMLGHAGDMAG | DRB1*15:02 | 2 | 9.333 | 0.010 |
YQAWQAQWNQAMEDL | DQB1*03:19 | 2 | 18.667 | 0.002 |