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Fig. 12 | BMC Immunology

Fig. 12

From: Long-term leukocyte reconstitution in NSG mice transplanted with human cord blood hematopoietic stem and progenitor cells

Fig. 12

Example for estimated sample sizes required for animal experimentation. a: percentage of CD4+ T cells (of CD45 + CD3+ cells) in hu NSG mice was determined before (baseline) and at week 8 after infection with the R4-tropic HIV strain NL4-3. b: figure depicts total sample sizes required to detect a decline in the percentage of CD4+ T cells between 0% and 25% for different power assumptions. Calculations were based on a mean increase in the percentage of CD4+ T cells of 11.7% (SD: 12.4%) between week 16 and week 24 post-transplantation

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