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Fig. 1 | BMC Immunology

Fig. 1

From: The cytokine polymorphisms affecting Th1/Th2 increase the susceptibility to, and severity of, chronic ITP

Fig. 1

Th1/Th2 ratio of patients with chronic ITP and healthy controls. a Th1/Th2 ratio of patients with chronic ITP was significantly higher than healthy controls (median, 31.4 vs. 17.8, P = 0.002). b Platelet count (×109⁄L) at diagnosis of chronic ITP with Th1/Th2 ratio 20 was significantly lower than that with Th1/Th2 ratio < 20 (median, 22.5 vs. 53.0, P = 0.02). c Minimum platelet count (×109⁄L) of chronic ITP with Th1/Th2 ratio 20 was significantly lower than that with Th1/Th2 ratio < 20 (median, 13.0 vs. 28.0, P = 0.04). d Th1/Th2 ratio of patients with the IFN-γ +874 non-AA genotype was significantly higher than that of the AA genotype (median, 71.5 vs. 27.5, P = 0.04). Th1/Th2 ratio of controls was similar in IFN-γ +874 polymorphism. e Th1/Th2 ratio of patients with the IFN-γR −611 non-AA genotype was significantly higher than that of the AA genotype (median, 78.5 vs. 28.4, P = 0.01). Th1/Th2 ratio of controls was similar in IFN-γR −611 polymorphism. f Th1/Th2 ratio of both patients and controls with the IL-4–590 non-CC genotype was not significantly different from that of the CC genotype. g Th1/Th2 ratio of both patients and controls with the IL-4Rα Q576R non-QQ genotype was not significantly different from that of the QQ genotype

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