Fig. 1
From: Autoantibodies against BAFF, APRIL or IL21 - an alternative pathogenesis for antibody-deficiencies?
Results of Screening-ELISA. In this Box-and-Whiskers-Plot the bottom and top of the box represent the first and third quartiles of the dataset, the band inside the median, and the whiskers show the minimum and maximum values. In Panel (a), anti-BAFF ELISA read-outs show a significant difference between healthy donors and the CVID and sIgAD cohort. Similar results were obtained with anti-APRIL-ELISA (Panel b) and anti-IL-21 ELISA (Panel c). The dashed line marks a cut-off value for each ELISA, defined as the healthy donor mean + 2 standard deviation, above which samples were considered positive