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Fig. 4 | BMC Immunology

Fig. 4

From: JAK inhibitor has the amelioration effect in lupus-prone mice: the involvement of IFN signature gene downregulation

Fig. 4

TOFA suppressed cytokine expression in kidneys and whole blood from BWF1. (a) Il6, Il2, (b) Ifnα, and Ifnγ expression in kidneys. (c) Total RNA extraction from whole-blood samples and evaluation of (c, left) Ifnα and (c, right) Ifnγ expression. Each represents [TOFA (n = 13); TOFA + DEXA (n = 14–15); DEXA (n = 7–8); and control (n = 11–13)]. *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001 (vs. control mice)

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