Table 1 Experimental conditions from which DNA microarray data was generated

Model system

Unstimulated (“Ctr”)

10⁶/mL N. meningitidis (“Nm”)

10⁶/mL N. meningitidis + 25 ng/mL IL-10 (“Nm + IL-10”)

25 ng/mL IL-10 (“IL-10”)^a

Patient plasma system

Plasma from patients with meningococcal meningitis or mild meningococcemia (“low LPS plasma”)

Plasma from patients with severe meningococcal sepsis or septic shock, depleted for IL-10 (“IL-10 immunodepleted plasma”)

Plasma from patients with severe meningococcal sepsis or septic shock (“patient plasma with IL-10”)

Plasma from patients with meningococcal meningitis or mild meningococcemia, depleted for IL-10 (“low LPS plasma immunodepleted for IL-10”)^a