BMC Immunology

Table 2 Natural killer cell activities and cytokine production from PBMCs

From: Hyporesponsiveness of natural killer cells and impaired inflammatory responses in critically ill patients

	Control group (n = 24)	ICU patient (n = 24)	p
NK cell activity
NK cell activity E:T = 10:1 (%)^∮	27.4 ± 2.37	16.4 ± 1.99	0.002
NK cell activity E:T = 5:1 (%)^∮	20.8 ± 1.85	13.1 ± 2.15	0.006
NK cell activity E:T = 2.5:1 (%)^∮	20.1 ± 2.20	13.0 ± 1.94	0.011
NK cell activity E:T = 1.25:1 (%)^∮	23.1 ± 2.24	15.1 ± 2.19	0.013
Non-stimulated PBMC
TNF-α (pg/mL)^∮	2.03 ± 0.31	5.26 ± 1.48	0.103
IL-6 (pg/mL)^∮	12.1 ± 3.57	19.9 ± 3.29	0.039
IL-1β (pg/mL)^∮	0.70 ± 0.24	2.58 ± 0.51	0.002
PBMC (LPS 5 ng/mL)
TNF-α (pg/mL)^∮	299.7 ± 42.5	173.0 ± 39.2	0.007
IL-6 (pg/mL)^∮	2045.3 ± 341.9	685.9 ± 238.8	0.025
IL-1β (pg/mL)^∮	22.5 ± 5.90	18.0 ± 6.79	0.304
PBMC (LPS 10 ng/mL)
TNF-α (pg/mL)^∮	322.3 ± 49.2	210.5 ± 57.7	0.015
IL-6 (pg/mL)^∮	2479.2 ± 369.2	498.9 ± 108.4	<0.001
IL-1β (pg/mL)^∮	24.7 ± 3.77	15.2 ± 4.92	0.001

Mean ± SE.^∮tested by logarithmic transformation. p: derived from independent t-test

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