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Fig. 5 | BMC Immunology

Fig. 5

From: Renal allograft rejection, lymphocyte infiltration, and de novo donor-specific antibodies in a novel model of non-adherence to immunosuppressive therapy

Fig. 5

a-i Quantitative RT-PCR analysis of chemokine and chemokine receptor expression from renal grafts after syngeneic or allogeneic transplantation treated with CyA for 6 or 28 days, or CyA on alternating days until d28. mRNA expression of target genes was normalized to the house-keeping gene HPRT and x-fold expression in comparison to syngeneic Tx d6 is shown. In (a) CCL19, (b) CCL20, (c) CCL21, (d) Lymphotoxin-β, (e) CCL5, (f) CXCL13, (g) CCL2, (h) CCR7, and (i) CCR5. Data is shown as mean ± SEM. Groups consisted of at least 6 animals. Statistical analysis is shown (Mann-Whitney U Test). Significance is shown as *p < 0.05 compared to “SynTxd6”, and # p < 0.05 compared to “Txd28CyAalt”

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