Table 3 Association between M1 and M2 macrophages number within cancer islets and stroma and clinicopathological characteristics
| Â | M1 macrophages | M2 macrophages | ||
|---|---|---|---|---|
Islets | Stroma | Islets | Stroma | |
Gender: | ||||
 Female | 33.5 (10–47) | 71 (44–100) | 16.5 (4–41) | 80.5 (43–112) |
 Male | 26 (10–67) | 72 (38–111) | 22 (4–54) | 89.5 (40–167) |
Age (years): | ||||
 < 65 | 29 (10–67) | 72 (38–108) | 24 (4–40) | 90 (40–112) |
 ≥ 65 | 26 (10–47) | 72 (41–111) | 19 (4–54) | 87 (43–167) |
Smoking status: | ||||
 Smokers | 26 (10–67) | 74 (38–111)* | 22.5 (4–54) | 90 (40–167)* |
 Non-smokers | 32 (10–47) | 58 (42–100) | 17.5 (4–41) | 78.5 (43–104) |
Histological NSCLC type: | ||||
 Adenocarcinoma | 33.5 (10–51)*# | 64.5 (41–111) | 22 (4–40) | 86.5 (43–115) |
 Squamous cell carcinoma | 22.5 (10–67) | 75.5 (48–101) | 20.5 (5–54) | 93.5 (40–167) |
 Other | 27.5 (23–47) | 69 (38–100) | 24.5 (11–41) | 89 (60–99) |
Stage: | ||||
 IA-IB | 26 (10–45) | 66 (41–111) | 20 (4–35) | 95 (60–167) |
 IIA-IIB | 29 (10–45) | 72 (43–108) | 23 (4–54) | 86 (53–119) |
 IIIA-IIIB | 29 (11–67) | 76 (38–101) | 20 (5–39) | 91 (40–109) |
pT status: | ||||
 pT1a-2b | 29 (10–47) | 71 (41–111) | 21.5 (4–54) | 87.5 (53–167) |
 pT3–4 | 24 (11–67) | 75 (38–108) | 21 (4–41) | 86.5 (40–108) |
Lymph node status: | ||||
 Negative (N0) | 26 (10–45) | 64 (41–111)* | 20 (4–41) | 90 (60–167) |
 Positive (N1-N3) | 29 (11–67) | 77 (38–101) | 22 (5–54) | 87 (40–119) |
Differentiation: | ||||
 Poor | 26.5 (10–67) | 71 (41–111) | 23.5 (4–54) | 92.5 (43–167) |
 Well-moderate | 29 (10–51) | 72.5 (38–101) | 19 (4–40) | 87 (40–119) |
COPD: | ||||
 Present | 26 (10–67) | 68.5 (38–111) | 22 (4–41) | 87 (40–115) |
 Absent | 29 (15–51) | 77 (43–101) | 19 (4–54) | 90.5 (51–167) |