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Table 4 Comparison of using peptides based ELISA and traditional methods in TB diagnose

From: Utility of dominant epitopes derived from cell-wall protein LppZ for immunodiagnostic of pulmonary tuberculosis

  

pep-LppZ-1

pep-LppZ-13

TB Subgroups

N

Positive N (Cutoff > 13.5)

Sensitive

Positive N (Cutoff > 16.3)

Sensitive

Smear1 +

48

22

45.8%

20

41.7%

Smear -

8

4

50.0%

3

37.5%

Culture2 +

88

46

52.3%

43

48.9%

Culture -

11

6

54.5%

4

36.4%

IGRA3 +

80

38

47.5%

32

40.0%

IGRA -

13

8

61.5%

6

46.2%

  1. 1Smear: sputum smear detection for TB bacteria
  2. 2Culture: bacteria culture
  3. 3IGRA: IFN-γ release assay (T-SPOT.TB)