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Table 4 Comparison of using peptides based ELISA and traditional methods in TB diagnose

From: Utility of dominant epitopes derived from cell-wall protein LppZ for immunodiagnostic of pulmonary tuberculosis

   pep-LppZ-1 pep-LppZ-13
TB Subgroups N Positive N (Cutoff > 13.5) Sensitive Positive N (Cutoff > 16.3) Sensitive
Smear1 + 48 22 45.8% 20 41.7%
Smear - 8 4 50.0% 3 37.5%
Culture2 + 88 46 52.3% 43 48.9%
Culture - 11 6 54.5% 4 36.4%
IGRA3 + 80 38 47.5% 32 40.0%
IGRA - 13 8 61.5% 6 46.2%
  1. 1Smear: sputum smear detection for TB bacteria
  2. 2Culture: bacteria culture
  3. 3IGRA: IFN-γ release assay (T-SPOT.TB)