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Table 5 Improvement of detection rate by using pep-LppZ-1 and pep-LppZ-13

From: Utility of dominant epitopes derived from cell-wall protein LppZ for immunodiagnostic of pulmonary tuberculosis

Diagnose method N Positive N Detection rate
Sputum smear 122 48 39.3%
Smear + pep-LppZ-11 86 70.5%
Smear + pep-LppZ-132 81 66.4%
Smear + pep-LppZ-1/13 89 73.0%
Bacteria culture 88 72.1%
Culture + pep-LppZ-1 102 83.6%
Culture + pep-LppZ-13 98 80.3%
Culture + pep-LppZ-1/13   102 83.6%
IGRA test 93(29 missing) 80 86.0%
IGRA test + pep-LppZ-1 88 94.6%
IGRA test + pep-LppZ-13 86 92.5%
IGRA test + pep-LppZ-1/13 89 95.7%
  1. 1the threshold of pep-LppZ-1 detection is > 13.5
  2. 2the threshold of pep-LppZ-13 detection is > 16.3
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BMC Immunology

ISSN: 1471-2172

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