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Table 5 Improvement of detection rate by using pep-LppZ-1 and pep-LppZ-13

From: Utility of dominant epitopes derived from cell-wall protein LppZ for immunodiagnostic of pulmonary tuberculosis

Diagnose method

N

Positive N

Detection rate

Sputum smear

122

48

39.3%

Smear + pep-LppZ-11

86

70.5%

Smear + pep-LppZ-132

81

66.4%

Smear + pep-LppZ-1/13

89

73.0%

Bacteria culture

88

72.1%

Culture + pep-LppZ-1

102

83.6%

Culture + pep-LppZ-13

98

80.3%

Culture + pep-LppZ-1/13

 

102

83.6%

IGRA test

93(29 missing)

80

86.0%

IGRA test + pep-LppZ-1

88

94.6%

IGRA test + pep-LppZ-13

86

92.5%

IGRA test + pep-LppZ-1/13

89

95.7%

  1. 1the threshold of pep-LppZ-1 detection is > 13.5
  2. 2the threshold of pep-LppZ-13 detection is > 16.3