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Fig. 5 | BMC Immunology

Fig. 5

From: Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-γ

Fig. 5

Influence of cytokine milieu. NK cells were activated overnight in serum-free medium in the absence or presence of FMKp with or without different cytokine combinations (no cytokines; IL-2/IL-18; IL-12/IL-15/IL-18). iDC were matured in presence or absence of these NK cell-derived supernatants for 48 h. DC-derived cytokine and chemokine secretion was determined in cell-free supernanant by CBA. a Cytokine profile. b Chemokine profile. Data are shown as mean + SEM of n ≥ 4 independent experiments. Mann-Whitney U test comparing absence and presence of NK cell-derived supernatant (white vs. gray bars). * P≤0.05, ** P≤0.01

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