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Table 2 Comparison of kidney function among different IF grades of immunoglobulin and complement

From: A pilot and comparative study between pathological and serological levels of immunoglobulin and complement among three kinds of primary glomerulonephritis

Parameters

n

eGFR, ml/min per 1.73m2

Ptrend

Urea, mmol/L

Ptrend

Crea, μmol/L

Ptrend

IgG

Neg

126

89.7(84.1–95.4)

0.054

6.33(5.72–6.94)

0.167

100.7(92.0–109.5)

2.94E-5

+

33

98.9(88.5–109.3)

5.42(4.32–6.51)

85.0(74.6–95.4)

++

77

101.7(96.5–107.0)

5.49(4.98–6.00)

76.0(70.7–81.3)

IgM

Neg

230

95.2(91.4–99.0)

0.359

5.93(5.52–6.33)

0.326

90.0(84.6–95.4)

0.133

+

6

83.6(49.2–117.9)

5.97(4.84–7.09)

107.7(67.2–148.2)

IgA

Neg

139

102.1(98.1–106.1)

8.99E-4

5.75(5.21–6.27)

0.036

77.5(73.7–81.4)

2.06E-6

+

37

75.8(64.6–87.0)

6.34(5.55–7.13)

117.7(101.5–133.8)

++

60

90.1(81.8–98.5)

6.09(5.25–6.93)

103.6(89.1–118.2)

C3

Neg

114

99.4(94.2–104.7)

0.080

5.89(5.29–6.49)

0.269

85.3(78.7–92.0)

0.195

+

108

90.3(84.4–96.2)

6.07(5.49–6.65)

96.1(87.2–104.9)

++

14

94.4(80.8–108.0)

5.18(4.14–6.22)

89.0(64.7–113.4)

C4

Neg

236

94.9(91.2–98.7)

–

5.93(5.53–6.32)

–

90.5(85.1–95.8)

–

  1. Results were shown as mean(95% CI). eGFR was estimated by MDRD formula [1]
  2. IF intensity grades of IgG, IgM,IgA, C3 and C4 were defined as following: Neg: negative, +: positive, ++: strong positive