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Table 3 Comparison of IF intensity grades and serum levels of IgG between IgAN and MN

From: A pilot and comparative study between pathological and serological levels of immunoglobulin and complement among three kinds of primary glomerulonephritis

 

Parameters

IgG pathological grade

P value

Ptrend

Neg

+

++

  

IgAN

N(female)

71(26)

17(4)

–

0.234

–

Age

39.7(36.9–42.4)

32.1(27.9–36.3)

–

0.014

0.015

Un

6.52(5.74–7.29)

5.24(4.58–5.91)

–

0.129

0.120

Cr

117.3(103.4–131.1)

88.1(76.3–99.9)

–

0.117

0.048

eGFR

78.6(70.8–86.5)

102.6(89.1–116.1)

–

0.005

0.007

sIgG

1013.2(942.7–1083.7)

1024.4(871.7–1177.1)

–

0.779

0.889

MN

N(female)

7(3)

16(8)

77(30)

0.712

–

Age

51.0(42.2–59.8)

51.3(42.0–60.6)

47.4(43.9–50.8)

0.554

0.301

Un

4.90(3.77–6.03)

5.68(3.22–8.14)

5.50(4.99–6.02)

0.555

0.703

Cr

64.2(53.8--74.5)

82.8(62.7–103.0)

76.0(70.6–81.3)

0.383

0.601

eGFR

108.8(96.2–121.5)

94.0(75.5–112.5)

101.6(96.4–106.9)

0.667

0.950

sIgG

777.9(529.1–1026.6)

727.7(561.9–893.5)

582.9(525.0–640.7)

0.034

0.014

  1. Pathological grades were IF intensity grades of IgG, IgM,IgA, C3 and C4 were defined as following: Neg: negative, +: positive, ++: strong positive. P value showed difference among Neg, positive (+) and (++)(analyzed by nonparametric tests-Kruskal-Wallis H test). Ptrend showed serum immunoglobulin or compliment trends with their enhanced Pathological grade. P and Ptrend values under 0.05 were considered as cut-off values as statistically significant differences