Fig. 1From: The expression analysis of Fra-1 gene and IL-11 protein in Iranian patients with ulcerative colitisThe IL-11/fra-1 pathway that in colonic tissue of patients with UC is designed. Environmental effects trigger innate immune system to produce ROS and inflammatory mediators. IL-11 can be released to reconstruct injury as a result of the activated IL-11/fra-1 pathwayBack to article page