Skip to main content
Fig. 2 | BMC Immunology

Fig. 2

From: Treponema pallidum promotes macrophage polarization and activates the NLRP3 inflammasome pathway to induce interleukin-1β production

Fig. 2

T. pallidum (at different MOIs) promotes NLRP3 inflammasome activation and IL-1β expression in macrophages. a, mRNA levels of NLRP3. b, mRNA levels of caspase-1. c, mRNA levels of IL-1β. d, Protein levels of IL-1β. e and f, Protein levels of NLRP3, active caspase-1, and IL-1β determined through a western blotting analysis. M0 macrophages treated with PBS served as the control group. The values represent the means±SDs of triplicate trials and are representative of three independent experiments. The western blotting results are representative of three independent experiments. Student’s t-test was used to compare the different MOI treatments with the control group. ** P < 0.01; ***P < 0.001

Back to article page

BMC Immunology

ISSN: 1471-2172

Contact us