Fig. 1
Elevated serum IL-17A, IL-23 and IL-17F levels in the C. neoformans–infected mice. C57BL/6 mice (n = 2 per group) were intranasally inoculated with 1 × 105 cells of four different strains of C. neoformans (H99, S48B, S68B and H4), serum were collected after 14 days for Bio-plex cytokine array. Mock denotes control mice intranasally administrated with equal volume of PBS. Different cytokines in the TH17 panel, (a) IL-17A, (b) IL-17F, (c) IL-21, (d) IL-22, (e) IL-23, (f) IL-31, (g) IL-33 and (h) MIP-3α were measured. Data are representative of two independent experiments. *P < 0.05, **P < 0.01, n.s.: not significant or P ≥ 0.05, by Student’s t-test