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Fig. 5 | BMC Immunology

Fig. 5

From: Altered endotoxin responsiveness in healthy children with Down syndrome

Fig. 5

Neutrophil and monocyte TLR-4 expression in response to LPS and melatonin in children with DS versus controls: Samples were treated with Lipopolysaccharide (LPS), Melatonin (Mel), Lipopolysaccharide and melatonin (LPS + Mel) and Lipopolysaccharide (LPS) versus Lipopolysaccharide and melatonin (LPS/ LPS + Mel) and expressed as fold changes in mean channel fluorescence (MFI). a Neutrophil TLR-4 (DS n = 19; Controls n = 10); b Total monocyte TLR-4 (DS n = 22; Controls n = 15); c Classical monocyte TLR-4 (DS n = 16; Controls n = 15); d Intermediate monocyte TLR-4 (DS n = 15; Controls n = 14); e Non-classical monocyte TLR-4 (DS n = 16; Controls n = 20)

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