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Table 3 Bivariate and multivariate analysis of associated risk factors of virological failure on ART/AIDs patients attending University of Gondar Referral Hospital 2017

From: Prevalence and associated factors of treatment failure among HIV/AIDS patients on HAART attending University of Gondar Referral Hospital Northwest Ethiopia

Variables Virological failure COR(95%CI) AOR(95%CI) P value
Yes No
Age 18–29 15 (27.8%) 39 (72.2%) 4.53 (1.52–13.49) 2.18 (0.28–16.98) 0.456
30–39 22 (13.0%) 147 (87.0%) 1.76 (.63–4.88) 1.15 (0.25–0.45) 0.858
40–49 20 (14.7%) 116 (85.3%) 2.03(0.72–5.69) 0.91 (0.19–4.44) 0.907
> = 50 5 (7.8%) 59 (92.2%)    Ref
Marital status Married 19 (9.1%) 190 (90.9%) 0.32 (.16–.62) 0.61 (0.15-2.44) 0.347
Divorced 14 (17.3%) 67 (82.7%) 0.67(.32–1.41) 2.52 (0.61-10.45) 0.243
Widowed 6 (16.7%) 30 (83.3%) 0.64 (.23–1.73) 1.59 (0.27-9.55) 0.665
Single 23 (23.7%) 74 (76.3%)    Ref
Reason of switching Tb + pregnant 6 (15.4%) 33 (84.6%) 1.45 (.50–4.18) 1.15 (0.37–3.57) 0.811
Default + age 8 (53.3%) 7 (46.7%) 9.14 (2.81–29.71) 7.20 (1.99-25.94) 0.003*
Toxicity 12 (11.1%) 96 (88.9%)    Ref
Current CD4 count <=199 2659.1% 18 (40.9%) 23.43 (9.50–57.77) 10.09 (2.47–41.29) 0.001*
200-349 19 (17.3%) 91 (82.7%) 3.38 (1.46–7.80) 2.94 (0.86–10.07) 0.085
350–499 8 (7.0%) 106 (93.0%) 1.22 (.45–3.27) 0.83 (0.18-3.80) 0.807
> = 500 9 (5.8%) 146 (85.3%)    Ref
  1. Note: *Has significant association
  2. Those variables with in p value < 0.2 under bivariate analysis were included with in multivariate analysis
  3. COR crude odds ratio, AOR adjusted odds ratio, Ref reference, CI confidence interval p significant value