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Table 3 Bivariate and multivariate analysis of associated risk factors of virological failure on ART/AIDs patients attending University of Gondar Referral Hospital 2017

From: Prevalence and associated factors of treatment failure among HIV/AIDS patients on HAART attending University of Gondar Referral Hospital Northwest Ethiopia

Variables

Virological failure

COR(95%CI)

AOR(95%CI)

P value

Yes

No

Age

18–29

15 (27.8%)

39 (72.2%)

4.53 (1.52–13.49)

2.18 (0.28–16.98)

0.456

30–39

22 (13.0%)

147 (87.0%)

1.76 (.63–4.88)

1.15 (0.25–0.45)

0.858

40–49

20 (14.7%)

116 (85.3%)

2.03(0.72–5.69)

0.91 (0.19–4.44)

0.907

> = 50

5 (7.8%)

59 (92.2%)

  

Ref

Marital status

Married

19 (9.1%)

190 (90.9%)

0.32 (.16–.62)

0.61 (0.15-2.44)

0.347

Divorced

14 (17.3%)

67 (82.7%)

0.67(.32–1.41)

2.52 (0.61-10.45)

0.243

Widowed

6 (16.7%)

30 (83.3%)

0.64 (.23–1.73)

1.59 (0.27-9.55)

0.665

Single

23 (23.7%)

74 (76.3%)

  

Ref

Reason of switching

Tb + pregnant

6 (15.4%)

33 (84.6%)

1.45 (.50–4.18)

1.15 (0.37–3.57)

0.811

Default + age

8 (53.3%)

7 (46.7%)

9.14 (2.81–29.71)

7.20 (1.99-25.94)

0.003*

Toxicity

12 (11.1%)

96 (88.9%)

  

Ref

Current CD4 count

<=199

2659.1%

18 (40.9%)

23.43 (9.50–57.77)

10.09 (2.47–41.29)

0.001*

200-349

19 (17.3%)

91 (82.7%)

3.38 (1.46–7.80)

2.94 (0.86–10.07)

0.085

350–499

8 (7.0%)

106 (93.0%)

1.22 (.45–3.27)

0.83 (0.18-3.80)

0.807

> = 500

9 (5.8%)

146 (85.3%)

  

Ref

  1. Note: *Has significant association
  2. Those variables with in p value < 0.2 under bivariate analysis were included with in multivariate analysis
  3. COR crude odds ratio, AOR adjusted odds ratio, Ref reference, CI confidence interval p significant value