|
Variables
|
Treatment failure
|
COR (95%CI)
|
AOR(95%CI)
|
P value
|
|---|
|
Yes
|
No
|
|---|
|
Age
|
18–29
|
19(35%)
|
35(65%)
|
2.93 (1.22–7.04)
|
1.59 (0.54–4.72)
|
0.398
|
|
30–39
|
31(18%)
|
138(82%)
|
1.21(0.56–2.64)
|
1.13 (0.49–2.61)
|
0.772
|
|
40–49
|
26(19%)
|
110(81%)
|
1.28(0.57–2.84)
|
1.31 (0.56–3.04)
|
0.530
|
|
> = 50
|
10(16%)
|
54(84%)
|
Ref
| |
Ref
|
|
Educational status
|
No formal education
|
26(22%)
|
95(79%)
|
3.65 (1.05–12.75)
|
3.89(1.10–13.77)
|
.035*
|
|
primary school
|
26 (22%)
|
91(78%)
|
3.81 (1.09–13.32)
|
3.730(1.06–13.18)
|
.041*
|
|
secondary school
|
31 (22%)
|
111(78%)
|
3.72 (1.08–12.86)
|
2.93(0.83–10.38)
|
.096
|
|
Tertiary
|
3 (7%)
|
40(93%)
|
Ref
| | |
|
Duration of ART in yrs.
|
< 6
|
39(24%)
|
123(76%)
|
1.44 (0.89–2.33)
|
2.1 (1.12–3.81)
|
0.021*
|
|
6
|
47(18%)
|
214(82%)
| | |
Ref
|
|
Initial regimen
|
D4T + 3TC + NVP
|
18 (23%)
|
60(77%)
|
0.08 (0.01–0.71)
|
0.10 (0.01–1.06)
|
0.056
|
|
D4T + 3TC+ EFV
|
2 (7%)
|
27(93%)
|
0.02 (0.001–0.25)
|
0.03 (0.002–0.37)
|
0.007*
|
|
AZT +3TC + NVP
|
31 (20%)
|
125(80%)
|
0.06 (0.01–0.57)
|
0.07 (0.01–0.72)
|
0.025*
|
|
AZT + 3TC + EFV
|
4(13%)
|
26(87%)
|
0.04 (0.003–0.44)
|
0.05 (0.004–0.57)
|
0.016*
|
|
TDF + 3TC + EFV
|
14(16%)
|
73(84%)
|
0.05 (0.01–0.46)
|
0.04 (0.004–0.46)
|
0.009*
|
|
TDF + 3TC + NVP
|
9 (29%)
|
22(71%)
|
0.102 (0.01–1.045)
|
0.11 (0.01–1.25)
|
0.075
|
|
D4T + 3TC + NVP(4a) child regimen
|
4 (57%)
|
3(43%)
|
0.33 (0.02–4.736)
|
0.32 (0.02–4.76)
|
0.408
|
|
AZT + 3TC + NVP(4c) child regimen
|
4 (80%)
|
1(20%)
| | |
Ref
|
|
AZT +3TC + NVP
|
18(30%)
|
43(71%)
|
Ref
| | |
- Note: * Has significant association
- Those variables with in p value < 0.2 under bivariate analysis were included with in multivariate analysis
- COR crude odds ratio, AOR adjusted odds ratio, Ref reference, CI confidence interval, p significant value, D4T Stavudine, TDF TenofovirDisoproxilFumarate, AZT/ 3TC Zidovudine/Lamivudine, EFV Efavirenze, NVP Nevirapined, di Didanosine
