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Table 5 Bivariate vs multivariate analysis of treatment failure on adult HIV/AIDS patients attending University of Gondar Referral Hospital 2017

From: Prevalence and associated factors of treatment failure among HIV/AIDS patients on HAART attending University of Gondar Referral Hospital Northwest Ethiopia

Variables Treatment failure COR (95%CI) AOR(95%CI) P value
Yes No
Age 18–29 19(35%) 35(65%) 2.93 (1.22–7.04) 1.59 (0.54–4.72) 0.398
30–39 31(18%) 138(82%) 1.21(0.56–2.64) 1.13 (0.49–2.61) 0.772
40–49 26(19%) 110(81%) 1.28(0.57–2.84) 1.31 (0.56–3.04) 0.530
> = 50 10(16%) 54(84%) Ref   Ref
Educational status No formal education 26(22%) 95(79%) 3.65 (1.05–12.75) 3.89(1.10–13.77) .035*
primary school 26 (22%) 91(78%) 3.81 (1.09–13.32) 3.730(1.06–13.18) .041*
secondary school 31 (22%) 111(78%) 3.72 (1.08–12.86) 2.93(0.83–10.38) .096
Tertiary 3 (7%) 40(93%) Ref   
Duration of ART in yrs. <  6 39(24%) 123(76%) 1.44 (0.89–2.33) 2.1 (1.12–3.81) 0.021*
6 47(18%) 214(82%)    Ref
Initial regimen D4T + 3TC + NVP 18 (23%) 60(77%) 0.08 (0.01–0.71) 0.10 (0.01–1.06) 0.056
D4T + 3TC+ EFV 2 (7%) 27(93%) 0.02 (0.001–0.25) 0.03 (0.002–0.37) 0.007*
AZT +3TC + NVP 31 (20%) 125(80%) 0.06 (0.01–0.57) 0.07 (0.01–0.72) 0.025*
AZT + 3TC + EFV 4(13%) 26(87%) 0.04 (0.003–0.44) 0.05 (0.004–0.57) 0.016*
TDF + 3TC + EFV 14(16%) 73(84%) 0.05 (0.01–0.46) 0.04 (0.004–0.46) 0.009*
TDF + 3TC + NVP 9 (29%) 22(71%) 0.102 (0.01–1.045) 0.11 (0.01–1.25) 0.075
D4T + 3TC + NVP(4a) child regimen 4 (57%) 3(43%) 0.33 (0.02–4.736) 0.32 (0.02–4.76) 0.408
AZT + 3TC + NVP(4c) child regimen 4 (80%) 1(20%)    Ref
AZT +3TC + NVP 18(30%) 43(71%) Ref   
  1. Note: * Has significant association
  2. Those variables with in p value < 0.2 under bivariate analysis were included with in multivariate analysis
  3. COR crude odds ratio, AOR adjusted odds ratio, Ref reference, CI confidence interval, p significant value, D4T Stavudine, TDF TenofovirDisoproxilFumarate, AZT/ 3TC Zidovudine/Lamivudine, EFV Efavirenze, NVP Nevirapined, di Didanosine