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Fig. 5 | BMC Immunology

Fig. 5

From: Patients with idiopathic recurrent miscarriage have abnormally high TGFß+ blood NK, NKT and T cells in the presence of abnormally low TGFß plasma levels

Fig. 5

IL4+, TGFß1+, IL10+ and IFNy+ NK cells before and after stimulation with K562 in-vitro. PBMC of iRM patients, kidney transplant recipients > 3 months post-transplant, kidney transplant recipients < 3 months post-transplant, ESRD patients and HC were incubated with tumor cell line K562 using an E:T ratio of 5:1. K562 stimulates particularly NK cells. Proportions of IL4+, TGFß1+, IFNy+ and IL10+ NK cells were measured before and after stimulation in the cell cultures. iRM patients and kidney transplant recipients > 3 months post-transplant showed an increase of IFNy+ NK cells after stimulation, the latter, in addition, an increase of IL4+ NK cells (for all p < 0.050). Number of patients tested for IFNy+ and IL10+ and in brackets IL4+ and TGFß1+ NK cells: 3 (2) HC, 4 (4) ESRD, 3 (1) early and 8 (6) late post-transplant and 6 (4) iRM patients

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BMC Immunology

ISSN: 1471-2172

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