Table 1 Demographic data of patients and healthy controls
HC (n = 35) | Late post-Tx (n = 37) | Early post-Tx (n = 10) | ESRD (n = 34) | iRM (n = 33) | |
|---|---|---|---|---|---|
Ages (years, median, SD) | 44 (13) | 55 (10) | 58 (12) | 52 (14) | 34 (4) |
Days post-transplant (median, range) | – | 1602 (95–3786) | 54 (7–93) | – | – |
Sex (n, %) | |||||
Female | 19 (54%) | 14 (38%) | 3 (30%) | 15 (44%) | 33 (100%) |
Male | 16 (46%) | 23 (62%) | 7 (70%) | 19 (56%) | 0 |
End stage renal disease (n, %) | |||||
Chronic glomerulonephritis | – | 3 (8%) | 2 (20%) | 7 (21%) | – |
Diabetes | – | 3 (8%) | 0 | 2 (6%) | – |
Hypertension/ischemic | – | 2 (5%) | 1 (10%) | 1 (3%) | – |
Nephrosclerosis | – | 2 (5%) | 0 | 5 (15%) | – |
Polycystic | – | 10 (27%) | 4 (40%) | 7 (21%) | – |
IgA nephropathy | – | 6 (16%) | 0 | 5 (15%) | – |
Others | – | 11 (30%) | 3 (30%) | 7 (21%) | – |
Graft No. (n, %) | |||||
First | – | 35 (95%) | 9 (90%) | – | – |
Second | – | 2 (5%) | 1 (10%) | – | – |
Donor (n, %) | |||||
Living | – | 26 (70%) | 5 (50%) | – | – |
Deceased | – | 11 (30%) | 5 (50%) | – | – |
Cold ischemia time (n, %) | |||||
< 3 h | – | 26 (70%) | 6 (60%) | – | – |
> 3 h | – | 11 (30%) | 4 (40%) | – | – |
Serum creatinine (n, %) | |||||
< 2 mg/dl | – | 33 (89%) | 8 (80%) | – | – |
> 2 mg/dl | – | 4 (11%) | 2 (20%) | 34 (100%) | – |
GFR (n, %) | |||||
< 35 ml/min | – | 3 (8%) | 2 (20%) | 34 (100%) | – |
35–50 ml/min | – | 12 (32%) | 8 (80%) | – | – |
> 50 ml/min | – | 22 (60%) | 0 | – | – |
HLA-ABDR mismatch > 3 (n, %) | – | 11 (30%) | 4 (40%) | – | – |
CMV IgG+ recipients (n, %) | – | 16 (43%) | 8 (80%) | – | – |
CMV IgG+ donors (n, %) | – | 18 (49%) | 8 (80%) | – | – |