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Table 1 Characteristics and medication details for the subset of patients included in the HLA class 1 SAB data seta

From: A novel approach reveals that HLA class 1 single antigen bead-signatures provide a means of high-accuracy pre-transplant risk assessment of acute cellular rejection in renal transplantation

 

ACR

Control

p-value

Number of kidney transplant recipients

34

18

–

Age at time of transplantation (years)

57.9 ± 11.0

51.6 ± 11.6

0.04

Body mass index at time of transplantation (kg/m2)

27.7 ± 5.4

24.2 ± 4.2

0.01

Gender

 Female

17 (50.0%)

7 (38.9%)

nsb

 Male

17 (50.0%)

11 (61.1%)

Type of donor

 Living

7 (20.6%)

4 (22.2%)

nsc

 Deceased

27 (79.4%)

14 (77.8%)

Re-transplantation

3 (8.8%)

0 (0.0%)

nsc

HLA-A Mismatchesd

 0

11 (32.4%)

9 (50.0%)

nsc

 1

18 (52.9%)

8 (44.4%)

 2

5 (14.7%)

1 (5.6%)

HLA-B Mismatchesd

 0

3 (8.8%)

4 (22.2%)

nsc

 1

18 (52.9%)

11 (61.1%)

 2

13 (38.2%)

3 (16.7%)

HLA-DR Mismatches

 0

3 (8.8%)

7 (38.9%)

0.03c

 1

20 (58.8%)

9 (50.0%)

 2

11 (32.4%)

2 (11.1%)

PRA = 0%

31 (91.2%)

16 (88.9%)

nsc

Therapeutic Arm

 A

12 (35.3%)

6 (33.3%)

nsc

 B

10 (29.4%)

3 (16.7%)

 C

12 (35.3%)

9 (50.0%)

Cold ischemia time: only deceased donors (min)

739 ± 295

637 ± 302

ns

  1. aData are given as mean ± standard deviation for quantitative variables and as number (frequency) for categorical variables. P values for quantitative variables were calculated by Mann-Whitney U test, for categorical variables either chi-squared (b) or Fisher’s exact test (c) were employed. (d) According to Fisher’s exact test, there is also no statistically significant differences between the ACR and Control groups when HLA-A and HLA-B mismatches are combined into one group