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Table 2 Table summarizing multiple linear regressions for IgG againist PfEBA-175. Increase in age, body weight and Hb level increased the concentration of IgG against PfEBA-175 by 0.501, 0.103 and 1.262 ng/ml respectively in children with HbSS but the increase was not statistically significant. On the other hand, there was a decrease in IgG concentration against PfEBA-175 by 0.0093 ng/ml with an increase in age but body weight and Hb level increased the IgG concentration by 0.01 and 0.046 ng/ml respectively although both decrease and increase were not statistically significant in children with HbAA

From: Immunoglobulin G responses against falciparum malaria specific antigens are higher in children with homozygous sickle cell trait than those with normal hemoglobin

IgG against Hemoglobin type Factor B P - value
PfEBA-175 (ng/ml) HbSS Age (year) 0.501 0.582
Body weight (kg) 0.103 0.282
Hb level (g/dl) 1.262 1.086
  HbAA Age (year) −0.093 0.335
Body weight (kg) 0.010 0.733
Hb level (g/dl) 0.046 0.768