Fig. 1

Regulation of CD44-related effector genes in the middle ear (ME) during the course of an episode of acute otitis media (OM) in the WT mouse. The kinetics of gene expression provide evidence regarding their function. Genes showing upregulation more than 5-fold above that observed in uninfected MEs (0 h) are illustrated. Results for all significantly regulated genes, as well as variability of expression, are presented in the Additional file 1: Table S1.