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Fig. 3 | BMC Immunology

Fig. 3

From: Lack of the hyaluronan receptor CD44 affects the course of bacterial otitis media and reduces leukocyte recruitment to the middle ear

Fig. 3

Hyperplasia of the ME mucosa after NTHi inoculation. a Mucosal histology in WT and CD44 KO mice during the course of OM. For most times, a representative example is presented. However, at day 10, where there was wide variation in ME responses, an example of persistent OM is shown. b Quantitative comparison of mucosal hyperplasia shows significantly decreased mucosal thickness at day 2 after NTHi inoculation in mice with CD44 deficiency. From day 7, resolution of mucosal hyperplasia is delayed compared to WT mice. For this and subsequent figures * = P < 0.05; ** = P < 0.01, and N = 6–8 ears

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BMC Immunology

ISSN: 1471-2172

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