Fig. 5

Leukocyte numbers measured in ME infiltrates in CD44^−/− and WT mice. a Neutrophils show reduced influx in CD44^−/− mice. The difference was significant at day 2 after NTHi inoculation. At day 10, the number of neutrophils increased again in CD44^−/− mice. b Numbers of macrophage were higher in CD44^−/− mice than WT mice throughout the study period. Significantly larger number of macrophage were found in mice with CD44 deficiency at day 2 and 3