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Fig. 1 | BMC Immunology

Fig. 1

From: A comprehensive autoantigen-ome of autoimmune liver diseases identified from dermatan sulfate affinity enrichment of liver tissue proteins

Fig. 1

Model illustrating our hypothesis that binding affinity to dermatan sulfate is a distinct biochemical property characterizing (a small subset of) human proteins (estimated at ~ 1%) that can become human autoantigens, whereas the majority of proteins (estimated at ~ 99%) that lack binding affinity have a much lower propensity to become targets of autoimmunity

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