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Table 1 Liver proteins with strong DS-affinity

From: A comprehensive autoantigen-ome of autoimmune liver diseases identified from dermatan sulfate affinity enrichment of liver tissue proteins

a    ANA (antinuclear autoantigens) Ref.
10 IPI00329998.3 H4 Histone H4 [8]
6 IPI00114642.4 Hist1h2bj Histone H2B type 1-F/J/L [9]
5 IPI00153400.2 H2afj Histone H2A.J [9]
5 IPI00111957.3 Hist1h2ba Histone H2B type 1-A [9]
4 IPI00137852.5 H2afy Core histone macro-H2A.1 [10]
2 IPI00404590.1 H1f0 Histone H1.0 [11]
3 IPI00119220.1 Snrpd2 Small nuclear ribonucleoprotein Sm D2 [12]
2 IPI00114052.1 Snrpb Small nuclear ribonucleoprotein-associated protein B [13]
2 IPI00122350.4 Snrpa U1 small nuclear ribonucleoprotein A [14]
2 IPI00133955.1 Snrpe Small nuclear ribonucleoprotein E [15]
3 IPI00131988.1 Mrpl49 39S ribosomal protein L49, mitochondria [16]
3 IPI00311236.1 Rpl7 60S ribosomal protein L7 [17]
2 IPI00122421.5 Rpl27 60S ribosomal protein L27 [18]
2 IPI00222549.6 Rpl30 60S ribosomal protein L30 [16]
3 IPI00124287.1 Pabpc1 Polyadenylate-binding protein [19]
2 IPI00119959.1 Banf1 Barrier-to-autointegration factor [20]
    SMA (anti-smooth muscle autoantigens) / Cytoskeleton  
6 IPI00753793.2 Spna2 Isoform 2 of Spectrin alpha chain [21]
5 IPI00123181.4 Myh9 Myosin-9 [22]
2 IPI00109044.8 G15Rik Myosin light chain, regulatory B-like [23]
2 IPI00354819.5 Myl6 Isoform Smooth muscle of Myosin light chain 6 [24]
2 IPI00230435.1 Lmna Isoform C2 of Lamin-A [25]
    AMA (anti-mitochondrial autoantigens)  
13 IPI00319992.1 Hspa5 78 kDa glucose-regulated protein (Grp78) [26]
13 IPI00114209.1 Glud1 Glutamate dehydrogenase 1, mitochondria [27, 28]
11 IPI00131424.3 Cpt2 Carnitine O-palmitoyltransferase 2, mitochondria  
6 IPI00133903.1 Hspa9 Stress-70 protein, mitochondria (Grp75) [29]
3 IPI00111908.8 Cps1 Carbamoyl-phosphate synthase [ammonia], mitochondria  
3 IPI00273146.1 Chdh Choline dehydrogenase, mitochondria  
2 IPI00129577.1 Aifm1 Apoptosis-inducing factor 1 (Aif, Pdcd8, programmed cell death protein 8), mitochondria [30]
    LKM (liver-kidney microsomal autoantigens)  
3 IPI00111936.1 Ugt1a9 UDP-glucuronosyltransferase 1-9 (bilirubin-specific) [31]
3 IPI00112322.2 Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 [32]
2 IPI00230113.5 Cyb5 Microsomal cytochrome b5 [33]
2 IPI00131771.3 Cox6c Cytochrome c oxidase subunit 6c  
2 IPI00169666.3 Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B3 [32]
2 IPI00230108.6 Pdia3 Protein disulfide-isomerase A [34]
2 IPI00134746.5 Ass1 Argininosuccinate synthase  
2 IPI00387289.3 Ces3 Carboxylesterase [35]
    Peroxisomal proteins  
3 IPI00112549.1 Acsl1 Long-chain-fatty-acid-CoA ligase  
2 IPI00312058.5 Cat Catalase [36, 37]
2 IPI00223367.5 Uox Uricase  
2 IPI00125325.1 Decr2 Peroxisomal 2,4-dienoyl-CoA reductase  
2 IPI00125813.1 Dpp4 Dipeptidyl peptidase (CD26) [38, 39]
  1. aColumns left to right: Number of peptides identified for the protein by mass spectrometry; Protein ID; Gene name; Protein name; Reference (if any) reporting autoantibodies induced by the protein
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BMC Immunology

ISSN: 1471-2172

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