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Table 2 Liver proteins with moderate DS-affinity

From: A comprehensive autoantigen-ome of autoimmune liver diseases identified from dermatan sulfate affinity enrichment of liver tissue proteins

a    ANA (antinuclear autoantigens) Ref.
8 IPI00230730.4 Hist2h3b Histone H3.2 [41]
4 IPI00223713.5 Hist1h1c Histone H1.2 [42]
2 IPI00459318.1 Hist1h2bp Putative uncharacterized protein, histone [9]
2 IPI00136632.3 H2afy3 Histone H2A member Y3 [43]
2 IPI00320149.2 H2afv Histone H2A member V [9]
6 IPI00308706.4 Rpl5 60S ribosomal protein L5  
5 IPI00127085.6 Rpl10a 60S ribosomal protein L10a  
3 IPI00555113.2 Rpl18 60S ribosomal protein L18  
3 IPI00138892.2 Uba52 Ubiquitin-60S ribosomal protein L40  
2 IPI00122598.3 EG382723 Similar to ribosomal protein L10  
5 IPI00339468.4 Dhx9 Isoform 2 of ATP-dependent RNA helicase, DNA helicase II [44]
4 IPI00121596.3 Prpf8 Pre-mRNA-processing-splicing factor 8  
3 IPI00109764.2 Top1 DNA topoisomerase 1 (Scl-70) [45]
2 IPI00322749.3 Snrpd1 Small nuclear ribonucleoprotein Sm D1 [46]
2 IPI00120162.1 Csnk2a1 Casein kinase II subunit alpha [17]
    SMA (anti-smooth muscle autoantigens) / Cytoskeleton  
6 IPI00400300.1 Lmna Isoform C of Lamin-A [47]
4 IPI00113886.1 Lmnb2 Isoform B3 of Lamin-B [48]
2 IPI00126191.5 Lmnb2 Isoform B2 of Lamin-B [49]
2 IPI00113824.1 Hspg2 Basement membrane-specific heparan sulfate proteoglycan core protein [50]
    AMA (anti-mitochondrial autoantigens)  
5 IPI00331555.2 Bckdha Branched chain keto acid dehydrogenase E1, alpha polypeptide (mitochondrion matrix) [51]
5 IPI00111877.1 Ssbp1 Single-stranded DNA-binding protein, mitochondria  
4 IPI00153144.3 Suox Sulfite oxidase, mitochondria [52]
3 IPI00133208.3 Hspa1l Heat shock 70 kDa protein 1L [53]
2 IPI00323357.3 Hspa8 Heat shock cognate 71 kDa protein [54]
3 IPI00420718.4 Hmgcs2 Hydroxymethylglutaryl-CoA synthase, mitochondria [27]
3 IPI00223092.5 Hadha Trifunctional enzyme subunit alpha, mitochondria  
3 IPI00135651.1 Slc25a13 Calcium-binding mitochondrial carrier protein Aralar2  
3 IPI00111885.1 Uqcrc1 Cytochrome b-c1 complex subunit 1, mitochondria [33]
3 IPI00132799.4 C1qbp Complement component 1 q subcomponent binding protein  
2 IPI00127841.3 Slc25a5 ADP/ATP translocase (mitochondrion inner membrane)  
2 IPI00387379.1 Decr1 2,4-dienoyl-CoA reductase, mitochondria  
    LKM (liver-kidney microsomal autoantigens)  
6 IPI00117914.3 Arg1 Arginase-1 [55]
6 IPI00115679.1 Ganab Isoform 2 of Neutral alpha-glucosidase A [56]
4 IPI00621548.2 Por NADPH-cytochrome P450 reductase [57]
4 IPI00134691.3 Ugt1a1 UDP-glucuronosyltransferase 1-1 [58]
2 IPI00110556.1 Cyp2e1 Cytochrome P450 2E1 [59, 60]
2 IPI00321644.3 Cyp2d26 Cytochrome P450 2D26 (mouse) (LKM1 human) [31]
    Peroxisomal proteins  
6 IPI00127558.3 Acox1 Peroxisomal acyl-coenzyme A oxidase  
6 IPI00127276.1 Ehhadh Enoyl-Coenzyme A hydratase/3-hydroxyacyl CoA dehydrogenase (peroxisomal bifunctional enzyme) [16]
2 IPI00331628.5 Hsd17b4 Peroxisomal multifunctional enzyme type (17 beta-hydroxysteroid dehydrogenase type 4) [61]
    Miscellaneous  
4 IPI00115599.6 Hsd11b1 Corticosteroid 11-beta-dehydrogenase isozyme  
3 IPI00117705.1 Ddost Dolichyl-diphosphooligosaccharide-protein glycosyltransferase 48 kDa subunit  
3 IPI00313236.3 Slc27a5 Bile acyl-CoA synthetase  
2 IPI00309035.2 Rpn1 Dolichyl-diphosphooligosaccharide-protein glycosyltransferase subunit 1 (ribophorin 1)  
2 IPI00127016.1 Hsd17b6 Hydroxysteroid 17-beta dehydrogenase [62]
2 IPI00130985.1 Rdh7 Retinol dehydrogenase  
  1. aColumns left to right: Number of peptides identified for the protein by mass spectrometry; Protein ID; Gene name; Protein name; Reference (if any) reporting autoantibodies induced by the protein
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BMC Immunology

ISSN: 1471-2172

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