TY - JOUR AU - Hao, Jian AU - Lv, Tiegang AU - Xu, Liping AU - Ran, Mao AU - Wu, Kaili PY - 2019 DA - 2019/06/27 TI - Macrophage migration inhibitory factor is involved in antineutrophil cytoplasmic antibody-mediated activation of C5a-primed neutrophils JO - BMC Immunology SP - 22 VL - 20 IS - 1 AB - C5a is important for antineutrophil cytoplasmic antibody (ANCA)-mediated activation of neutrophils. The present study aimed to assess the role of macrophage migration inhibitory factor (MIF) in ANCA-mediated activation of C5a-primed neutrophils. The effects of MIF on ANCA-mediated neutrophil respiratory burst and degranulation were determined. In addition, the effect of a MIF antagonist on the activation of C5a-primed neutrophils was assessed. SN - 1471-2172 UR - https://doi.org/10.1186/s12865-019-0306-z DO - 10.1186/s12865-019-0306-z ID - Hao2019 ER -