Table 6 Percentage growth inhibition in day 70 and day 140 at 6 mg/mL rabbit IgG for the two laboratory strains (FCR3 and NF54)
From: Identification of adjuvants for clinical trials performed with Plasmodium falciparum AMA1 in rabbits
Group | FCR3 day 70 | FCR3 day 140 | NF54 day 70 | NF54 day 140 |
|---|---|---|---|---|
Stable o/w Emulsion (SE) | 22.5 (13.9 to 31.0) | 0.8 (−10.5 to 12.1) | 12.6 (1.8 to 23.4) | 3.1 (−2.8 to 9.0) |
SE-Glucopyranosyl Lipid A (GLA) | 14.1 (7.7 to 20.5) | −1.2 (− 13.0 to 10.7) | 5.3 (1.2 to 9.4) | 5.6 (−5.3 to 16.5) |
Liposomes | 4.6 (−10.1 to 19.3) | −0.6 (− 13.7 to 12.5) | 7.2 (3.3 to 11.0) | 2.8 (− 0.5 to 6.0) |
Liposomes-GLA | 18.9 (−2.0 to 39.8) | −3.2 (− 17.4 to 11.0) | 6.4 (− 0.8 to 13.7) | 1.9 (− 5.6 to 9.3) |
CoVaccine HT™ | 61.2 (45.7 to 76.7) | 25.1 (16.3 to 34.0) | 42.9 (30.8 to 55.0) | −3.9 (− 33.1 to 25.3) |
ImSaVac-P | 31.4 (14.7 to 48.2) | −3.0 (−12.8 to 6.8) | 12.9 (7.3 to 18.6) | 4.9 (−6.2 to 15.9) |
ImSaVac-P o/w | 9.2 (1.5 to 17.0) | 8.3 (−10.7 to 27.3) | 5.3 (−2.2 to 12.8) | 5.0 (−3.0 to 13.0) |