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Table 1 Clinical characteristics of the studied groups

From: CD4+ T cell exhaustion revealed by high PD-1 and LAG-3 expression and the loss of helper T cell function in chronic hepatitis B

Variables CHB HC
Age 33.77 ± 1.09 35.45 ± 1.58
Gender (M/F) 62 (48/14) 60 (44/16)
HBeAg (+/−) 39/23 0/60
ALT (IU/L) 313.7 ± 53.31 20.88 ± 0.81
HBV-DNA (copies/mL) > 5.00 × 103 – 8.46 × 109 < 5.00 × 103
  1. Note: Data are presented as mean ± SEM. M/F male/female, HBeAg (+/−) HBeAg-positive and negative, CHB chronic hepatitis B patients, HC healthy control