Skip to main content

Table 2 Non-responders to pneumococcal serotypes in 59 index patients with subnormal IgGSc and normal total IgGa

From: Pneumococcal vaccination responses in adults with subnormal IgG subclass concentrations

S. pneumoniae serotype 1 3 4 8 9 12 14 19 23 26 51 56 57 58
Subnormal IgG1, % NR 20 20 100 25 25 75 29 29 71 66 20 50 0 17
Subnormal IgG1, % R 0 0 0 0 0 0 0 17 17 0 0 0 0 0
Subnormal IgG3, % NR 55 50 85 50 85 100 56 40 72 64 40 71 0 64
Subnormal IgG3, % R 11 0 25 0 0 50 0 7 27 25 13 0 0 0
Subnormal IgG1 + IgG3, % NR 50 50 100 0 0 100 17 66 66 0 25 50 0 66
Subnormal IgG1 + IgG3, % R 20 0 33 0 0 75 0 14 14 0 0 33 0 0
  1. aAbbreviations: IgGSc IgG subclass(es), NR Non-responders, R Responders. We defined responders as patients who achieved protective levels of serotype-specific IgG post- polyvalent pneumococcal polysaccharide vaccination